SH3BP4
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Official Full Name
SH3-domain binding protein 4 -
Overview
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. -
Synonyms
SH3BP4;SH3-domain binding protein 4;SH3 domain-binding protein 4;EH-binding protein 10;transferrin receptor trafficking protein;transferrin receptor-trafficking protein;TTP;BOG25
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SH3BP4 involved in several pathways and played different roles in them. We selected most pathways SH3BP4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SH3BP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SH3BP4 has several biochemical functions, for example, GDP-dissociation inhibitor activity,Ras GTPase binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SH3BP4 itself. We selected most functions SH3BP4 had, and list some proteins which have the same functions with SH3BP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | S100B,THBS1,AMOTL2,SMAD1,AGXT2L2,GSTM3,CEP170L,GOT2B,SLC22A1,CBS |
| GDP-dissociation inhibitor activity | GPSM2L,GDI1,GPSM1B,RANBP1,SH3BP4A,GPSM1,RGS14,ITGB1BP1 |
| Ras GTPase binding | RAPGEF6,MLLT4,RASGRP3,RAPGEF4,MAP2K1,PLCE1,CIB1,RGL3,MAPKAP1,RIN1 |
| protein binding | NLGN4X,CD70,KREMEN1,TBX5A,TNFRSF10A,ATP4B,RHEB,GPSM2,XPA,APLF |
Interacting Protein
SH3BP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SH3BP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SH3BP4.
YWHAG;TFRC;Dnm2;DNM2;PLEKHA1
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