SFRS5
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Official Full Name
SRSF5 serine/arginine-rich splicing factor 5 -
Overview
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
HRS;SFRS5;SRP40;serine/arginine-rich splicing factor 5;SR splicing factor 5;delayed-early protein HRS;pre-mRNA-splicing factor SRP40;splicing factor, arginine/serine-rich 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SFRS5-2623H | Recombinant Human SFRS5, His-tagged | E.coli | Human | His | 1-272aa |
|
Involved Pathway
SFRS5 involved in several pathways and played different roles in them. We selected most pathways SFRS5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SFRS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SFRS5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SFRS5 itself. We selected most functions SFRS5 had, and list some proteins which have the same functions with SFRS5. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SFRS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SFRS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SFRS5.
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References
- Fingert, JH; Alward, WL; et al. Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders. MOLECULAR VISION 16:596-601(2010).
- Hatakeyama, S; Sugihara, K; et al. Identification of mRNA splicing factors as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106:3095-3100(2009).
