SETD1B
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Official Full Name
SET domain containing 1B -
Overview
SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al.,;2007 (PubMed 17355966)). -
Synonyms
SETD1B;SET domain containing 1B;histone-lysine N-methyltransferase SETD1B;KIAA1076;KMT2G;Set1B;hSET1B;lysine N-methyltransferase 2G;SET domain-containing protein 1B;FLJ20803
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SETD1B-3213H | Recombinant Human SETD1B protein, His-tagged | E.coli | Human | His | 867-1044 aa | |
| SETD1B-14978M | Recombinant Mouse SETD1B Protein | Mammalian Cell | Mouse | His |
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| SETD1B-185H | Recombinant Human SET1B/WDR5/RbBP5/Ash2L/DPY-30 Complex Protein, His/GST-tagged | E.coli | Human | His&GST | 1629-1923;22-334;1-538;2-534;1-99 a.a. |
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| SETD1B-2366C | Recombinant Chicken SETD1B | Mammalian Cell | Chicken | His |
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| SETD1B-8066M | Recombinant Mouse SETD1B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SETD1B-8066M-B | Recombinant Mouse SETD1B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SETD1B involved in several pathways and played different roles in them. We selected most pathways SETD1B participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | ASH1L,HYKK.2,AGXT2L2,EHMT1,AADAT,GCDHA,ACAT1,SETDB2,SUV39H1A,MLL5 |
Protein Function
SETD1B has several biochemical functions, for example, RNA binding,histone-lysine N-methyltransferase activity,methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD1B itself. We selected most functions SETD1B had, and list some proteins which have the same functions with SETD1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity | MAT2AB,GLT25D2,ILF2,DNMT3,ILVBL,POLN,UGT5B2,SULT1ST7,SGK2A,ZDHHC16 |
| nucleotide binding | TNIKA,ACLYA,CAMK1DA,HSPA4L,LTB4R,RAB1BA,CLCN4-2,CRCP,NT5C1AA,NLRP9B |
| histone-lysine N-methyltransferase activity | SETD8,SETD2,KMT2A,SUV39H1B,PRDM9,SETD7,EZH2,EZH1,WHSC1L1,AAAS |
| RNA binding | HNRNPH1,PDCD4,NPM1,SRSF1B,RPL9,EIF4E1C,SRSF10,RBM4.1,TEP1,PRAC |
| methyltransferase activity | SMYD5,SUV39H1A,GAMT,ZCCHC4,FBLL1,METTL25,FAM86,THUMPD2,SMYD2A,C2orf56 |
| nucleic acid binding | ZFPM2A,VEZF1B,ZFP35,ARL14EP,SRSF1B,SALL1A,ZFP93,SP8B,ZNF644A,FOXP1B |
| molecular_function | GM4307,ZP3B,MURCA,XLR3B,DEFA3,CFHL1,WDR5B,BCL7BA,FAM102AB,JMJD4 |
Interacting Protein
SETD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD1B.
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References
- Qadota, H; McGaha, LA; et al. A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (obscurin) in Caenorhabditis elegans. MOLECULAR BIOLOGY OF THE CELL 19:2424-2432(2008).
- Wu, H; Zhang, GY; et al. T cell lines specific for a synthetic Heymann nephritis peptide derived from the receptor-associated protein. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 121:157-164(2000).
