SERPINI2
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Official Full Name
serpin peptidase inhibitor, clade I (pancpin), member 2 -
Overview
The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. -
Synonyms
SERPINI2;serpin peptidase inhibitor, clade I (pancpin), member 2;PI14, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2 , serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2;serpin I2;MEPI;PANCPIN;pancp
Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- Human Cell
- HEK293T
- Mammalian cells
- GST
- His
- His&T7
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SERPINI2-2603H | Recombinant Human SERPINI2, GST-tagged | E.coli | Human | GST | C-term-350aa | |
| SERPINI2-3865H | Recombinant Human SERPINI2 protein(Met1-Leu405), His-tagged | HEK293 | Human | His | 1-405 a.a. | |
| SERPINI2-59H | Recombinant Human SERPINI2 protein, T7/His-tagged | E.coli | Human | His&T7 | 19-405 a.a. |
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| SERPINI2-2083HCL | Recombinant Human SERPINI2 cell lysate | Human Cell | Human | Non |
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| SERPINI2-4961H | Recombinant Human SERPINI2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Serpini2-5794M | Recombinant Mouse Serpini2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SERPINI2-5918H | Recombinant Human SERPINI2 Protein (Ser19-Leu405), C-His tagged | Mammalian cells | Human | His | Ser19-Leu405 |
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| SERPINI2-997H | Recombinant Human SERPINI2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
SERPINI2 involved in several pathways and played different roles in them. We selected most pathways SERPINI2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPINI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SERPINI2 has several biochemical functions, for example, protein binding,serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPINI2 itself. We selected most functions SERPINI2 had, and list some proteins which have the same functions with SERPINI2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GLP1R,C19orf73,XBP1,ITPKB,CCDC13,ORC3L,CCDC68,PYYA,SNRPA1,HTR1B |
| serine-type endopeptidase inhibitor activity | MUG2,SERPING1,APLP2,WFIKKN1,SERPINB1L2,COL28A1,A1i3,SERPINA10,SPINK10,SERPINB3 |
Interacting Protein
SERPINI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPINI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPINI2.
UBQLN1;UBQLN1;SGTB;UBQLN4
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References
- Al-Husseini, W; Gondro, C; et al. Expression of candidate genes for residual feed intake in Angus cattle. ANIMAL GENETICS 45:12-19(2014).
- Al-Husseini, W; Gondro, C; et al. Hormonal growth implants affect feed efficiency and expression of residual feed intake-associated genes in beef cattle. ANIMAL PRODUCTION SCIENCE 54:550-556(2014).
