SEPT12

  • Official Full Name

    septin 12

  • Overview

    This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    SEPT12;septin 12;septin-12;FLJ25410;SEPT12;SEP12_HUMAN;Septin-12;Septin12
Cat.# Product name Source (Host) Species Tag Protein Length Price
SEPT12-5324R Recombinant Rat SEPT12 Protein Mammalian Cell Rat His
SEPT12-1964HCL Recombinant Human SEPT12 293 Cell Lysate HEK293 Human Non
SEPT12-4983R Recombinant Rat SEPT12 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
SEPT12-4983R-B Recombinant Rat SEPT12 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    SEPT12 involved in several pathways and played different roles in them. We selected most pathways SEPT12 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Bacterial invasion of epithelial cells VCL,ITGB1,RHOA,FN1,CTNNA3,PIK3CD,CLTC,CBLC,PIK3R2,CLTB

    Protein Function

    SEPT12 has several biochemical functions, for example, GDP binding,GTP binding,phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT12 itself. We selected most functions SEPT12 had, and list some proteins which have the same functions with SEPT12. You can find most of the proteins on our site.

    Function Related Protein
    phosphatidylinositol binding TNFAIP8L3,CCDC88A,GRB7,ITPR2,SH3YL1,SNX18B,SNX10A,SH3PXD2AA,SNX17,SNX1B
    GTP binding RAB3D,RND2,RAB39A,THG1L,RAB44,RHOJ,ARL5B,RAB12,RAB40B,SEPT10
    protein homodimerization activity LRRK2,AMICA1,USF2,BCL2L1,ATPIF1B,QPRT,UGT1A2,HEXB,ABP1,TCF3A
    GDP binding RAP2B,RAB4A,RAB14,TRIM23,RAB11B,RAB5C,EIF2B1,RAB8A,RHOA,RAB22A
    protein binding HIST1H2BE,CHRAC1,AHSA2,GNA13,KIF2C,LHX9,DCTN4,GPATCH4,RALYL,COLQ

    Interacting Protein

    SEPT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT12.

    SEPT6;SPAG4;SEPT1;LMNB1;SEPT4;OBSL1;PRM2;PCM1;NDC1

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