SEPHS2
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Official Full Name
selenophosphate synthetase 2 -
Overview
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3 UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. -
Synonyms
SEPHS2;selenophosphate synthetase 2;selenide, water dikinase 2;SPS2;selenium donor protein 2;selenophosphate synthase 2
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Yeast
- His
- Non
- Myc&DDK
- N-His&C-Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEPHS2-3342H | Recombinant Human SEPHS2 protein, His-tagged | E.coli | Human | His | 118-448 aa | |
| SEPHS2-14887M | Recombinant Mouse SEPHS2 Protein | Mammalian Cell | Mouse | His |
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| SEPHS2-584HCL | Recombinant Human SEPHS2 lysate | HEK293 | Human | Non |
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| SEPHS2-2161H | Recombinant Human SEPHS2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Sephs2-5765M | Recombinant Mouse Sephs2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SEPHS2-6443H | Recombinant Human SEPHS2 protein, His-tagged | Yeast | Human | His | 2-448aa(U60S) |
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| SEPHS2-6545H | Recombinant Human SEPHS2 protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 2-448aa(U60S) |
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| SEPHS2-770H | Recombinant Human SEPHS2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SEPHS2-8020M | Recombinant Mouse SEPHS2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SEPHS2-8020M-B | Recombinant Mouse SEPHS2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SEPHS2 involved in several pathways and played different roles in them. We selected most pathways SEPHS2 participated on our site, such as Selenocompound metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPHS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Selenocompound metabolism | PAPSS2A,MTR,PAPSS2,INMT,MARS,TXNRD1,SEPHS1,SCLY,TXNRD3,PAPSS1 |
| Metabolic pathways | glpK,B4GALNT1,NT5C3A,ATP6V0C,ATP6V1C2,CMPK2,TYMS,PIGB,AMT,MAOA |
Protein Function
SEPHS2 has several biochemical functions, for example, ATP binding,selenide, water dikinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPHS2 itself. We selected most functions SEPHS2 had, and list some proteins which have the same functions with SEPHS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| selenide, water dikinase activity | SEPHS1 |
| ATP binding | CHD1,DDX19B,DDX56,TTLL1,ACTR2,PTK7,SMCHD1,UBE2I,NLRP10,CAMK2B |
Interacting Protein
SEPHS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPHS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPHS2.
ARHGEF5
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