SEMG2
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Official Full Name
semenogelin II -
Overview
The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. -
Synonyms
SEMG2;semenogelin II;semenogelin-2;Semenogelin 2;SGII
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- Yeast
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEMG2-222H | Recombinant Human SEMG2 Protein, His-tagged | E.coli | Human | His |
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| SEMG2-4138R | Recombinant Rhesus monkey SEMG2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SEMG2-1976HCL | Recombinant Human SEMG2 293 Cell Lysate | HEK293 | Human | Non |
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| SEMG2-1825H | Recombinant Human SEMG2 Protein (24-582 aa), His-tagged | Yeast | Human | His | 24-582 aa |
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| SEMG2-2683H | Recombinant Human SEMG2 Protein, His-tagged | E.coli | Human | His | Leu261-Lys500 |
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| SEMG2-3955R | Recombinant Rhesus Macaque SEMG2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SEMG2-3955R-B | Recombinant Rhesus Macaque SEMG2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
SEMG2 involved in several pathways and played different roles in them. We selected most pathways SEMG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SEMG2 has several biochemical functions, for example, metal ion binding,protease binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMG2 itself. We selected most functions SEMG2 had, and list some proteins which have the same functions with SEMG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TERT,ARHGEF1,NOL3,DOCK2,SH2D3A,BCL11A,SKI,SOAT1,NLRP1,AUP1 |
| protease binding | LCN2,TIMP2,CFLAR,POLG,RFFL,SERPINA1E,COMP,PINK1,SERPINC1,ADAM8A |
| structural molecule activity | CLDN12,CLDN11,COL15A1B,KRT39,CLDN7,LMNB2,KRT6A,EPB41L3B,PNN,SPRR2E |
| metal ion binding | BSN,ZBTB7B,NDUFS2,HEPHL1,CISD3,ITGAX,ALDH1A2,NAALAD2,FGD4,SLX1B |
Interacting Protein
SEMG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMG2.
CDK10;PIK3R2;ESR1;ESR2
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References
- Laffan, A; Sawyert, I; et al. Evaluation of semen presumptive tests for use at crime scenes. MEDICINE SCIENCE AND THE LAW 51:11-17(2011).
- Terai, K; Yoshida, K; et al. Association of Seminal Plasma Motility Inhibitors/Semenogelins with Sperm in Asthenozoospermia-Infertile Men. UROLOGIA INTERNATIONALIS 85:209-215(2010).
