SEMA6C
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Official Full Name
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -
Overview
This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration. -
Synonyms
SEMA6C;sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C;semaphorin-6C;KIAA1869;m Sema Y2;m Sema Y;Sema Y;Semaphorin 6C [Precursor];Semaphorin Y;SEMAY;semaphorin-Y;OTTHUMP00000014154;OTTHUMP00000014155;OTTHUMP00000014156;OTTHUMP00000014157;m-SemaY;m-SemaY2
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- HEK293
- Mammalian cells
- Mammalian Cell
- His
- Fc
- Non
- His&Fc&Avi
Involved Pathway
SEMA6C involved in several pathways and played different roles in them. We selected most pathways SEMA6C participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA6C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | NRP2,AKAP9,NTN4,LIMK2,FRS2A,SCN3A,UNC5D,DUSP4,EPHB3,EGF |
Protein Function
SEMA6C has several biochemical functions, for example, chemorepellent activity,semaphorin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA6C itself. We selected most functions SEMA6C had, and list some proteins which have the same functions with SEMA6C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| semaphorin receptor binding | SEMA6E,SEMA6DL,SEMA3GB,SEMA3FA,SEMA4A,SEMA4B,SEMA6D,SEMA3E,SEMA3BL,SEMA3AB |
| chemorepellent activity | Sema3f,SEMA3FA,SEMA6B,SEMA3GB,SEMA5A,SEMA4C,SEMA6A,SEMA3C,SEMA6E,SEMA4B |
Interacting Protein
SEMA6C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA6C here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA6C.
Resources
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References
- Matsuoka, RL; Sun, LO; et al. Sema6B, Sema6C, and Sema6D Expression and Function during Mammalian Retinal Development. PLOS ONE 8:-(2013).
- Takamatsu, H; Takegahara, N; et al. Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. NATURE IMMUNOLOGY 11:594-U60(2010).
