SEMA4G
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Official Full Name
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G -
Overview
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SEMA4G;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G;semaphorin-4G;FLJ20590;KIAA1619;sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4G;semaphorin 4G;Semaphorin 4G precursor
Recombinant Proteins
- Human
- Mouse
- Mammalian cells
- Mammalian Cell
- HEK293
- Fc
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEMA4G-190H |
Active Recombinant Human SEMA4G Protein, Fc-tagged
|
Mammalian cells | Human | Fc | 18-675 a.a. |
|
| SEMA4G-14871M | Recombinant Mouse SEMA4G Protein | Mammalian Cell | Mouse | His |
|
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| SEMA4G-185H | Recombinant Human SEMA4G, His-tagged | HEK293 | Human | His | 18-680 a.a. |
|
| SEMA4G-1581HCL | Recombinant Human SEMA4G cell lysate | Human | Non |
|
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| SEMA4G-137H | Recombinant Human SEMA4G Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
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| SEMA4G-137H-B | Recombinant Human SEMA4G Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
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| SEMA4G-6095H | Recombinant Human SEMA4G Protein (Val18-Leu680), C-His tagged | Mammalian cells | Human | His | Val18-Leu680 |
|
| SEMA4G-8008M | Recombinant Mouse SEMA4G Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| SEMA4G-8008M-B | Recombinant Mouse SEMA4G Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SEMA4G involved in several pathways and played different roles in them. We selected most pathways SEMA4G participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA4G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SEMA4G has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA4G itself. We selected most functions SEMA4G had, and list some proteins which have the same functions with SEMA4G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
SEMA4G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA4G here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA4G.
Resources
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References
- Peltekova, IT; Hurteau-Millar, J; et al. Novel Interstitial Deletion of 10q24.3-25.1 Associated with Multiple Congenital Anomalies Including Lobar Holoprosencephaly, Cleft Lip and Palate, and Hypoplastic Kidneys. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:3132-3136(2014).
- Malik, MFA; Ye, L; et al. The plexin-B family and its role in cancer progression. HISTOLOGY AND HISTOPATHOLOGY 29:151-165(2014).
