SEMA3B
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Official Full Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -
Overview
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014] -
Synonyms
SEMA3B;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B;SemA;SEMA5;SEMAA;semaV;LUCA-1;semaphorin-3B;sema A(V);semaphorin A;semaphorin-V
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian cells
- Wheat Germ
- Mammalian Cell
- HEK293
- Insect Cell
- His
- Fc
- GST
- Non
- His&Fc&Avi
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEMA3B-3210H | Recombinant Human SEMA3B protein, His-tagged | E.coli | Human | His | 450-629 aa | |
| Sema3b-616M |
Active Recombinant Mouse Sema3b Protein, Fc Chimera
|
Mammalian cells | Mouse | Fc |
|
|
| SEMA3B-251H | Recombinant Human SEMA3B protein, GST-tagged | Wheat Germ | Human | GST | 651-748 a.a. |
|
| SEMA3B-6858Z | Recombinant Zebrafish SEMA3B | Mammalian Cell | Zebrafish | His |
|
|
| SEMA3B-1981HCL | Recombinant Human SEMA3B 293 Cell Lysate | HEK293 | Human | Non |
|
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| Sema3b-105M | Recombinant Mouse Sema3b Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
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| Sema3b-105M-B | Recombinant Mouse Sema3b Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| SEMA3B-1213H | Recombinant Human SEMA3B protein, His-tagged | E.coli | Human | His | 25-749aa |
|
| SEMA3B-2679H | Recombinant Human SEMA3B Protein, His-tagged | E.coli | Human | His | Pro573-Trp749 |
|
| SEMA3B-5900H | Recombinant Human SEMA3B protein, His&Myc-tagged | Insect Cell | Human | His&Myc | 25-749aa |
|
Involved Pathway
SEMA3B involved in several pathways and played different roles in them. We selected most pathways SEMA3B participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | Plxna2,MYL12A,EFNB2A,PPP3CA,CNKSR1,NFATC2,SPRED2,SCN2A,SLC14A2,SHB |
Protein Function
SEMA3B has several biochemical functions, for example, chemorepellent activity,neuropilin binding,semaphorin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA3B itself. We selected most functions SEMA3B had, and list some proteins which have the same functions with SEMA3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chemorepellent activity | UBE4A,NRG3,SEMA3C,SEMA6E,FLRT2,SEMA6D,SEMA6DL,SLIT2,SEMA4D,SEMA3GA |
| neuropilin binding | Sema3f,SEMA3E,SEMA3D,SEMA3C,SEMA3FA,SEMA3BL,SEMA4E,SEMA3H,SEMA3GA,SEMA3GB |
| semaphorin receptor binding | SEMA3BL,Sema3f,SEMA4BA,SEMA4C,SEMA6E,SEMA6B,SH3BGRL3,SEMA6C,SEMA3A,SEMA5B |
Interacting Protein
SEMA3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA3B here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA3B.
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