SEC24D
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Official Full Name
SEC24 family, member D -
Overview
Coat Protein Complex II (COPII) is composed of five cytosolic proteins: Sec23/24 complex, Sec13/31 complex, and Sar1. COPII coat is located at the ER/Golgi interface and is involved in transport of newly synthesized proteins from the ER to the Golgi appar -
Synonyms
SEC24D;SEC24 family, member D (S. cerevisiae);SEC24 (S. cerevisiae) related gene family, member D;protein transport protein Sec24D;KIAA0755;SEC24-related protein D;SEC24 related gene family, member D;FLJ43974
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEC24D-7750Z | Recombinant Zebrafish SEC24D | Mammalian Cell | Zebrafish | His |
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| SEC24D-1991HCL | Recombinant Human SEC24D 293 Cell Lysate | HEK293 | Human | Non |
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| Sec24d-5749M | Recombinant Mouse Sec24d Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
SEC24D involved in several pathways and played different roles in them. We selected most pathways SEC24D participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC24D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | ERO1LB,DNAJB1B,SYVN1,PDIA3,DNAJB12,PPP1R15A,LMAN1,DNAJC5GA,MBTPS2,STT3B |
Protein Function
SEC24D has several biochemical functions, for example, molecular_function,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC24D itself. We selected most functions SEC24D had, and list some proteins which have the same functions with SEC24D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | TNNI2B.2,ILVBL,NLRC3,CX34.4,ROMO1,ASB10,TMEM41AB,ZMYND17,PTGES3L,TMEM22 |
| zinc ion binding | CIZ1B,PAPLNB,RERE,ABLIM1,DHH,ZFP330,LHX8A,ADAM21,FTR67,BAZ2B |
| protein binding | BEND7,CACNG2,SIAH2,TOX4,GNMT,RFFL,FAM127B,MEX3C,P2RX4,LMAN1 |
Interacting Protein
SEC24D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC24D here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC24D.
SEC23B;EWSR1;SF3B4;SEC23A;TMED10;TMED2;WWP2;LMO4;CDK16;GCNT1;CDK18
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References
- Garbes, L; Kim, K; et al. Mutations in SEC24D, Encoding a Component of the COPII Machinery, Cause a Syndromic Form of Osteogenesis Imperfecta. AMERICAN JOURNAL OF HUMAN GENETICS 96:432-439(2015).
- Arribas-Gonzalez, E; de Juan-Sanz, J; et al. Molecular Basis of the Dominant Negative Effect of a Glycine Transporter 2 Mutation Associated with Hyperekplexia. JOURNAL OF BIOLOGICAL CHEMISTRY 290:2150-2165(2015).
