SEC23B
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Official Full Name
Sec23 homolog B -
Overview
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. -
Synonyms
SEC23B;Sec23 homolog B (S. cerevisiae);CDAN2, congenital dyserythropoietic anemia, type II , Sec23 (S. cerevisiae) homolog B;protein transport protein Sec23B;CDA II;CDAII;HEMPAS;SEC23-like protein B;SEC23-related protein B;transport protein SEC
Recombinant Proteins
- Zebrafish
- Chicken
- Mouse
- Cynomolgus
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SEC23B involved in several pathways and played different roles in them. We selected most pathways SEC23B participated on our site, such as Protein processing in endoplasmic reticulum,SREBP signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC23B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | SSR4,SEL1L2,VIMP,CRYAB,UBE2D2A,BAK1,SEC31B,UBE2D1B,HNF4B,MAN1A2 |
| SREBP signalling | INSIG2,RNF139,RBP4,DBI,INSIG1 |
Protein Function
SEC23B has several biochemical functions, for example, protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC23B itself. We selected most functions SEC23B had, and list some proteins which have the same functions with SEC23B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | MAN2C1,UBOX5,ADAM10A,MT1X,TP53,RFPL2,HE1A,RSPRY1,TRAF4B,TRIM33 |
| protein binding | KAT2A,SMYD2,RFC2,PACSIN2,FASTKD5,MAP2K1,TMEM119,XRN1,PHF10,ADORA2A |
Interacting Protein
SEC23B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC23B here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC23B.
SEC24D;HOXA3;DTX2;DTX2;SYNE4;CPSF7
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References
- Renella, R; Roberts, NA; et al. Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1 alpha localization in erythroblasts. BLOOD 117:6928-6938(2011).
