SCN4B
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Official Full Name
sodium channel, voltage-gated, type IV, beta subunit -
Overview
The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009] -
Synonyms
SCN4B;sodium channel, voltage-gated, type IV, beta subunit;LQT10;Navbeta4;sodium channel subunit beta-4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCN4B-5267R | Recombinant Rat SCN4B Protein | Mammalian Cell | Rat | His |
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| SCN4B-461H | Recombinant Human SCN4B Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SCN4B-4926R | Recombinant Rat SCN4B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SCN4B-4926R-B | Recombinant Rat SCN4B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Scn4b-5717M | Recombinant Mouse Scn4b Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
SCN4B involved in several pathways and played different roles in them. We selected most pathways SCN4B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SCN4B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SCN4B itself. We selected most functions SCN4B had, and list some proteins which have the same functions with SCN4B. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SCN4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN4B here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN4B.
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References
- Xiao, ML; Bosch, MK; et al. FGF14 localization and organization of the axon initial segment. MOLECULAR AND CELLULAR NEUROSCIENCE 56:393-403(2013).
- Pantazis, A; Savalli, N; et al. Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:18381-18386(2014).
