SCN10A
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Official Full Name
sodium channel, voltage-gated, type X, alpha subunit -
Overview
The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties;of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits.;This protein may be involved in the onset of pain associated with peripheral neuropathy. -
Synonyms
SCN10A;sodium channel, voltage-gated, type X, alpha subunit;sodium channel, voltage gated, type X, alpha polypeptide;sodium channel protein type 10 subunit alpha;hPN3;Nav1.8;PN3;SNS;peripheral nerve sodium channel 3;sodium channel protein type X
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCN10A-5258R | Recombinant Rat SCN10A Protein | Mammalian Cell | Rat | His |
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| SCN10A-4917R | Recombinant Rat SCN10A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SCN10A-4917R-B | Recombinant Rat SCN10A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SCN10A involved in several pathways and played different roles in them. We selected most pathways SCN10A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN10A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SCN10A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SCN10A itself. We selected most functions SCN10A had, and list some proteins which have the same functions with SCN10A. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
SCN10A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN10A here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN10A.
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References
- Cejudo-Roman, A; Pinto, FM; et al. The Voltage-Gated Sodium Channel Na(v)1.8 Is Expressed in Human Sperm. PLOS ONE 8:-(2013).
- Facer, P; Punjabi, PP; et al. Localisation of SCN10A Gene Product Na(v)1.8 and Novel Pain-Related Ion Channels in Human Heart. INTERNATIONAL HEART JOURNAL 52:146-152(2011).
- Bowsher, D; Woods, CG; et al. Absence of pain with hyperhidrosis: A new syndrome where vascular afferents may mediate cutaneous sensation. PAIN 147:287-298(2009).
