SCLY
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Official Full Name
selenocysteine lyase -
Overview
Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of;L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 (PubMed 10692412)). -
Synonyms
SCLY;selenocysteine lyase;putative selenocysteine lyase;SCL;hSCL
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SCLY involved in several pathways and played different roles in them. We selected most pathways SCLY participated on our site, such as Selenocompound metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCLY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Selenocompound metabolism | MTR,TXNRD2,CCBL1,PAPSS2A,SEPHS2,SEPSECS,SEPHS1,PAPSS2,TXNRD3,TXNRD1 |
| Metabolic pathways | PYGM,PLA2G4F,SDHDB,CYP4F3,ALDH1A2,PYGL,PCXB,POLR1E,PIK3C2A,GANC |
Protein Function
SCLY has several biochemical functions, for example, protein binding,selenocysteine lyase activity,transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCLY itself. We selected most functions SCLY had, and list some proteins which have the same functions with SCLY. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity | A3GALT2,UGT5E1,ZDHHC1,MLL5,NEK5,DNMT5,SUV39H1B,ZDHHC6,JAK2A,OXCT2B |
| protein binding | CTNND1,RB1,RNF139,PYGO2,EFNA3,PPP2R3C,ATXN2,GNG5,NEK1,VPS33A |
Interacting Protein
SCLY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCLY here. Most of them are supplied by our site. Hope this information will be useful for your research of SCLY.
TERF2IP;CREB3;yvmA;LNX2;Mcm3;Atp7a;Ncaph;TFG;EXOSC5;VPS18
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References
- Ye, H; Garifullina, GF; et al. The chloroplast NifS-like protein of Arabidopsis thaliana is required for iron-sulfur cluster formation in ferredoxin. PLANTA 220:602-608(2005).
- Rhee, SG; Cho, CS; et al. BLOT-BASED DETECTION OF DEHYDROALANINE-CONTAINING GLUTATHIONE PEROXIDASE WITH THE USE OF BIOTIN-CONJUGATED CYSTEAMINE. METHODS IN ENZYMOLOGY, VOL 474: THIOL REDOX TRANSITIONS IN CELL SIGNALING, PT B: CELLULAR LOCALIZATION AND SIGNALING 474:23-34(2010).
