SCD
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Official Full Name
stearoyl-CoA desaturase (delta-9-desaturase) -
Overview
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012] -
Synonyms
SCD;stearoyl-CoA desaturase (delta-9-desaturase);SCD1;FADS5;SCDOS;MSTP008;acyl-CoA desaturase;delta-9 desaturase;delta-9-desaturase;delta(9)-desaturase;fatty acid desaturase;predicted protein of HQ0998;stearoyl-CoA desaturase opposite strand
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- Sheep
- Bovine
- Mesocricetus auratus
- Goat
- Sus scrofa (Pig)
- Wheat Germ
- E.Coli or Yeast
- Mammalian Cell
- HEK293
- E.coli expression system
- E.coli
- In vitro E. coli expression system
- GST
- His
- Non
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCD-28H | Recombinant Human SCD protein, GST-tagged | Wheat Germ | Human | GST | 1-100 a.a. |
|
| SCD-3126H | Recombinant Human SCD, His-tagged | E.Coli or Yeast | Human | His | 359 |
|
| SCD-5246R | Recombinant Rat SCD Protein | Mammalian Cell | Rat | His |
|
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| SCD-6453C | Recombinant Chicken SCD | Mammalian Cell | Chicken | His |
|
|
| SCD-9849Z | Recombinant Zebrafish SCD | Mammalian Cell | Zebrafish | His |
|
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| SCD-2044HCL | Recombinant Human SCD 293 Cell Lysate | HEK293 | Human | Non |
|
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| RFL15797OF | Recombinant Full Length Sheep Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Sheep | His | Full L. Full Length of Mature Protein (2-359) |
|
| RFL19383BF | Recombinant Full Length Bovine Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length of Mature Protein (2-359) |
|
| RFL34573MF | Recombinant Full Length Mesocricetus Auratus Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Mesocricetus auratus | His | Full L. Full Length of Mature Protein (2-354) |
|
| RFL4212CF | Recombinant Full Length Goat Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Goat | His | Full L. Full Length of Mature Protein (2-359) |
|
| RFL4237SF | Recombinant Full Length Pig Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Sus scrofa (Pig) | His | Full L. Full Length (1-334) |
|
| RFL7559HF | Recombinant Full Length Human Acyl-Coa Desaturase(Scd) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-359aa) |
|
| SCD-2394H | Recombinant Human SCD protein, His-tagged | E.coli | Human | His | 1-359aa |
|
| SCD-2726H | Recombinant Human SCD Full Length Transmembrane protein (1-359 aa), His-tagged | In vitro E. coli expression system | Human | His | Full L. 1-359aa |
|
| scd-2743Z | Recombinant Zebrafish scd Protein, His&GST-tagged | E.coli | Zebrafish | His&GST | His87-Arg183 |
|
| SCD-4905R | Recombinant Rat SCD Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SCD-4905R-B | Recombinant Rat SCD Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
SCD involved in several pathways and played different roles in them. We selected most pathways SCD participated on our site, such as Biosynthesis of unsaturated fatty acids,Fatty acid metabolism,PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of unsaturated fatty acids | PECR,HSD17B12,ACOT2,ACAA1A,TECR,PTPLAD2,ACAA1,HADHAA,SCD5,ELOVL5 |
| PPAR signaling pathway | RXRG,RXRB,UBC,APOC3,PCK1,PLIN1,PDPK1,SLC27A1A,PCK2,ADIPOQ |
| Fatty acid metabolism | PPT1,EHHADH,ACSL3,HADHA,CPT1C,OXSM,ACADS,FADS2,ACSL3A,FASN |
| AMPK signaling pathway | LIPE,ADRa1A,PIK3R1,FOXO1,PPP2R5A,AKT1S1,RHEB,GYS2,PRKAB2,CREB3L3 |
Protein Function
SCD has several biochemical functions, for example, iron ion binding,oxidoreductase activity,stearoyl-CoA 9-desaturase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCD itself. We selected most functions SCD had, and list some proteins which have the same functions with SCD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion binding | PHF8,CYP2F1,PTGIS,CYP3A5,ALOX5,LTF,HBA-X,CYP3A25,CYP2AA12,CYP4A11 |
| oxidoreductase activity | NDOR1,CYBASC3,GPX5,PDHA1B,WWOX,SDR16C5B,DAO.1,HPDB,DHRS13A.3,CYP2AA8 |
| stearoyl-CoA 9-desaturase activity | FADS2,Scd1,Scd2,SCD5 |
Interacting Protein
SCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCD here. Most of them are supplied by our site. Hope this information will be useful for your research of SCD.
MYC;E2F3
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References
- Noizat-Pirenne, F; Habibi, A; et al. The use of rituximab to prevent severe delayed haemolytic transfusion reaction in immunized patients with sickle cell disease. VOX SANGUINIS 108:262-267(2015).
- Rieux, C; De Meyer, E; et al. Delayed hemolytic transfusion reaction in sicle cell disease patients: A new challenge for the Hemovigilance network. TRANSFUSION CLINIQUE ET BIOLOGIQUE 22:37-41(2015).
