SCAMP4
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Official Full Name
secretory carrier membrane protein 4 -
Overview
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane;trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central;transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is;mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to;function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 (PubMed 11050114)). -
Synonyms
SCAMP4;secretory carrier membrane protein 4;secretory carrier-associated membrane protein 4;FLJ33847;SCAMP-4;FLJ90105
Recombinant Proteins
- Zebrafish
- Rat
- Rice
- Human
- Arabidopsis thaliana
- Mus musculus
- Pongo Abelii
- Bovine
- Mouse
- Mammalian Cell
- E.coli expression system
- In vitro E. coli expression system
- HEK293
- His
- His&Fc&Avi
Involved Pathway
SCAMP4 involved in several pathways and played different roles in them. We selected most pathways SCAMP4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SCAMP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SCAMP4 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by SCAMP4 itself. We selected most functions SCAMP4 had, and list some proteins which have the same functions with SCAMP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | CCDC172,HEATR5A,ASB12B,TUSC2A,GPKOW,DCDC2C,PITPNAA,TECRL,RAD21L1,ZNF705D |
Interacting Protein
SCAMP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCAMP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCAMP4.
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References
- Hutter, V; Chau, DYS; et al. Digoxin net secretory transport in bronchial epithelial cell exclusively mediated by P-glycoprotein/MDR1. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 86:74-82(2014).
- Diering, GH; Church, J; et al. Secretory Carrier Membrane Protein 2 Regulates Cell-surface Targeting of Brain-enriched Na+/H+ Exchanger NHE5. JOURNAL OF BIOLOGICAL CHEMISTRY 284:13892-13903(2009).
