SCAMP2
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Official Full Name
secretory carrier membrane protein 2 -
Overview
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. -
Synonyms
SCAMP2;secretory carrier membrane protein 2;secretory carrier-associated membrane protein 2;OTTHUMP00000183476
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Mus musculus
- Arabidopsis thaliana
- Rice
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SCAMP2 involved in several pathways and played different roles in them. We selected most pathways SCAMP2 participated on our site, such as Arf6 trafficking events,Monoamine Transport,Serotonin Transporter Activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCAMP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Serotonin Transporter Activity | TPH2,TGFB1I1 |
| Monoamine Transport | FBXO32,DBH,TGFB1I1,TPH2,SYN1,UNC13B,HRH3 |
| Arf6 trafficking events | CPE,DNM2,EXOC6,CHRM2,EXOC1,EXOC5,CLTC,SPAG9,EDNRB,CTNND1 |
Protein Function
SCAMP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SCAMP2 itself. We selected most functions SCAMP2 had, and list some proteins which have the same functions with SCAMP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SLC30A3,TERF2,SYTL2,UBE2U,TSG101,PREP,MRAP,LILRB4,FPR1,UNC13A |
Interacting Protein
SCAMP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCAMP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCAMP2.
YWHAZ;ARIH2;ST3GAL3;q5neb3_fratt;pi3p;REEP5;NCAPH
Resources
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References
- Matthies, HJG; Han, Q; et al. Subcellular localization of the antidepressant-sensitive norepinephrine transporter. BMC NEUROSCIENCE 10:-(2009).
- Diering, GH; Church, J; et al. Secretory Carrier Membrane Protein 2 Regulates Cell-surface Targeting of Brain-enriched Na+/H+ Exchanger NHE5. JOURNAL OF BIOLOGICAL CHEMISTRY 284:13892-13903(2009).
- Lin, PJC; Williams, WP; et al. Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7. JOURNAL OF CELL SCIENCE 118:1885-1897(2005).
- Wu, TT; Castle, JD; et al. Evidence for colocalization and interaction between 37 and 39 kDa isoforms of secretory carrier membrane proteins (SCAMPs). JOURNAL OF CELL SCIENCE 110:1533-1541(1997).
