SART3
-
Official Full Name
squamous cell carcinoma antigen recognized -
Overview
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. -
Synonyms
SART3;squamous cell carcinoma antigen recognized;squamous cell carcinoma antigen recognised by T cells 3;squamous cell carcinoma antigen recognized by T-cells 3;KIAA0156;RP11 13G14;hSART 3;p110(nrb);RP11-13G14;Tat interacting protein of 110 kDa;TIP110;SART-3;hSART-3;tat-interacting protein of 110 kDa;P100;p110;DSAP1
Recombinant Proteins
- Mouse
- Zebrafish
- Rhesus macaque
- Human
- Mammalian Cell
- HEK293
- E.coli
- Yeast
- Mammalian cells
- HEK293T
- His
- Non
- His&SUMO
- Flag
- His&Fc&Avi
- GST
- Myc&DDK
Involved Pathway
SART3 involved in several pathways and played different roles in them. We selected most pathways SART3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SART3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SART3 has several biochemical functions, for example, U4 snRNA binding,NOT U4 snRNA binding,U6 snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SART3 itself. We selected most functions SART3 had, and list some proteins which have the same functions with SART3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| U6 snRNA binding | DDX39B,PRPF8,LSM8,LSM4,RBM22,EIF5A,LSM7,LSM2,PRPF4 |
| nucleotide binding | VDAC2,NOL8,U2SURP,GC3,ORC5,SBK1,RBMY1F,RBM4.3,HPRT1,DYRK1AA |
| ubiquitin-specific protease binding | SELS,PARK2,AMFR,RAD23A,DERL1,MARCH6,BAG6,VCP,VPS24,CHMP3 |
| protein binding | LINGO1,C20orf20,ACMSD,F3,EYA2,KLHL38,LOXL2,APBB3,HSFX1,EIF4A1 |
| histone binding | NCL,TBL1X,NPM2,SUPT6H,USP3,PHF21A,HIST1H4E,ELP2,HIST1H4M,HIST1H3G |
| poly(A) RNA binding | DDX56,CPNE3,SNRPB,METAP2,HUWE1,DDX55,PCSK9,LARP2,ZFP579,PPIG |
| U4 snRNA binding | DDX39B,PRPF31,NHP2L1,PRPF4 |
Interacting Protein
SART3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SART3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SART3.
RNPS1;PRPF4;PRPF3;PPIH;LSM8;SNRPB;LSM6;FRG1;C3orf17;CENPU;MEPCE;SRBD1;PRPF31;CMSS1;Nhp2l1
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