SAMD4A
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Official Full Name
sterile alpha motif domain containing 4A -
Overview
Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a;posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was;named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 (PubMed 16221671)). -
Synonyms
SAMD4A;sterile alpha motif domain containing 4A;SAMD4, sterile alpha motif domain containing 4;protein Smaug homolog 1;DKFZP434H0350;hSmaug1;KIAA1053;Smaug;smaug homolog (Drosophila);SMG;SMGA;SAMD4;Smaug 1;Smaug homolog;SMAUG1;Sterile alpha motif domain containing protein 4A;SAM domain-containing protein 4A
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SAMD4A-2503H | Recombinant Human SAMD4A, GST-tagged | E.coli | Human | GST | C-term-383aa | |
| SAMD4A-1558HCL | Recombinant Human SAMD4A cell lysate | Human | Non |
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| SAMD4A-4935H | Recombinant Human SAMD4A Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
SAMD4A involved in several pathways and played different roles in them. We selected most pathways SAMD4A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SAMD4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SAMD4A has several biochemical functions, for example, poly(A) RNA binding,protein binding,translation repressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SAMD4A itself. We selected most functions SAMD4A had, and list some proteins which have the same functions with SAMD4A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| translation repressor activity | PATL2,PAIP2,CIRBP,IREB2,EIF4EBP2,EIF4EBP3,TRIM71,SAMD4,EIF4EBP1 |
| poly(A) RNA binding | SSRP1,FAM32A,ZFP346,IFIT5,PPHLN1,MKI67,PPIA,XRN1,MFAP1,HNRPDL |
| protein binding | DNAJB2,RAB3IL1,ZMAT3,ABHD16A,ENTPD3,TRIM59,SPC25,EIF3A,F3,ATCAY |
Interacting Protein
SAMD4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SAMD4A here. Most of them are supplied by our site. Hope this information will be useful for your research of SAMD4A.
YWHAG;GOLGA2;NUTM1;SFN;hsdM;YWHAB
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References
- de Haro, M; Al-Ramahi, I; et al. Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy. PLOS GENETICS 9:-(2013).
- Ohta, Y; Nishiyama, A; et al. Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells. PHYSICAL REVIEW E 86:-(2012).
