Rbpjl
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Official Full Name
recombination signal binding protein for immunoglobulin kappa J region-like -
Overview
This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. -
Synonyms
RBPJL;SUHL;RBPSUHL;recombination signal binding protein for immunoglobulin kappa J region-like;recombining binding protein suppressor of hairless-like protein;transcription factor RBP-L
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RBPJL-2226H | Recombinant Human RBPJL, His-tagged | E.coli | Human | His | 428-517aa | |
| RBPJL-2452HCL | Recombinant Human RBPJL 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
Rbpjl involved in several pathways and played different roles in them. We selected most pathways Rbpjl participated on our site, such as Epstein-Barr virus infection,Notch Signaling Pathway,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rbpjl were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epstein-Barr virus infection | POLR2J,EIF2AK2,MAP2K7,SHFM1,NFKBIE,H2-Q10,HSPA1L,PLCG1,NUP214,YWHAB |
| Viral carcinogenesis | CDC42,VAC14,TBP,CASP8,HIST1H2BH,GTF2A1L,TTC6,HIST1H2BD,Casp3,HIST1H2BL |
| Notch signaling pathway | CIR1,JAG1A,DLL3,PSEN1,CTBP1,NOTCH1,NOTCH4,RBPJ,DLA,PTCRA |
Protein Function
Rbpjl has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin binding,transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Rbpjl itself. We selected most functions Rbpjl had, and list some proteins which have the same functions with Rbpjl. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | DLX4,YBX1,PAX5,PYDC3,MAFB,RBPJ,RELA,ELF4,PER1,CHD7 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | FOSL1A,JDP2,HIST2H3A,SREBF1,SFPI1,FOSL2,BATF2,FOS,RBPJB,SNAI3 |
| transcription factor activity, sequence-specific DNA binding | KLF17,HOXC4A,TFE3,CSRNP2,GTF2H4,HMGA1,TWIST2,ARNTL2,JUNBB,ELK3 |
| chromatin binding | UBTF,RELB,BRD2,TP63,MSH6,SMAD2,GM606,PHF8,POU1F1,SOD3 |
Interacting Protein
Rbpjl has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rbpjl here. Most of them are supplied by our site. Hope this information will be useful for your research of Rbpjl.
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References
- Danielsson, A; Ponten, F; et al. The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling. PLOS ONE 9:-(2014).
- Hale, MA; Swift, GH; et al. The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. DEVELOPMENT 141:3123-3133(2014).
