RYR3
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Official Full Name
ryanodine receptor 3 -
Overview
The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RYR3;ryanodine receptor 3;Brain ryanodine receptor calcium release channel;Brain ryanodine receptor-calcium release channel;Brain type ryanodine receptor;Brain-type ryanodine receptor;HBRR;RYR 3;RYR-3;RYR3_HUMAN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RYR3-359H | Recombinant Human RYR3 | Mammalian Cells | Human | His |
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| RYR3-7089C | Recombinant Chicken RYR3 | Mammalian Cells | Chicken | His |
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| RYR3-4020H | Recombinant Human RYR3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| RYR3-4020H-B | Recombinant Human RYR3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RYR3-790H | Recombinant Human RYR3 Protein (3934-4181 aa), His-tagged | E.coli | Human | His | 3934-4181 aa |
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Involved Pathway
RYR3 involved in several pathways and played different roles in them. We selected most pathways RYR3 participated on our site, such as Calcium signaling pathway,Circadian entrainment,Oxytocin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RYR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Circadian entrainment | PRKACB,GNG13,CALM4,PER1,MTNR1A,GNGT1,PRKCB,KCNJ6,GNG7,KCNJ5 |
| Salivary secretion | PRKCB,MUC5B,AMY1A,PRB1,BST1,PRKCA,GUCY1A3,PLCB4,ATP1A1,CALM1 |
| Alzheimers disease | NDUFS7,UQCRB,SDHB,GRIN2A,CALML3,ATP5D,SNCA,APH1B,UQCRQ,NDUFC2-KCTD14 |
| Calcium signaling pathway | TRHR,DRD1A,ITPKB,CALML3,CACNA1C,AVPR1B,STIM2,SLC25A5,EGFRA,EDNRBA |
| Oxytocin signaling pathway | CALML3,PIK3CA,TRPM2,CALM4,MAP2K5,PPP1R12A,PPP3CC,CACNG1,PRKACG,RYR1 |
Protein Function
RYR3 has several biochemical functions, for example, calcium ion binding,calcium-induced calcium release activity,calcium-release channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RYR3 itself. We selected most functions RYR3 had, and list some proteins which have the same functions with RYR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calmodulin binding | CNN1,PHKG1B,ATP2B1,SPTAN1,ARPP21,MYO1G,MYO1A,PHKG2,NETO2,EPB41B |
| ryanodine-sensitive calcium-release channel activity | RYR2,RYR1,RYR1B |
| calcium ion binding | AGRN,NCS1B,RCN2,PCDH2G28,CALRL2,PCDH19,SYT11A,VLDLR,EFCAB4B,PON1 |
| calcium-release channel activity | RASA3,RYR1,RYR2,TRPV1,JPH2,JPH3 |
| calcium-induced calcium release activity | RYR2,PKD2 |
Interacting Protein
RYR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RYR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RYR3.
HNF1A;dcyD
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