RT1-DA
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Official Full Name
RT1 class II, locus Da -
Overview
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein. -
Synonyms
RT1-DA;RT1 class II, locus Da;H2-Ea;Histocompatibility 2, class II antigen E alpha;MGC112637;MHC class II antigen RT1.D alpha chain;MHC class II RT1D alpha chain antigen;MHC RT1.u D alpha chain;RT1 class II, locus Da;RT1 D alpha;RT1 Du alpha;RT1-u;RT1-D alpha;RT1-Du alpha;MHC RT1.u-D-alpha chain;MHC class II RT1D alpha chain antigen;MHC class II antigen RT1.D alpha chain;histocompatibility 2, class II antigen E alpha;H2-Ea;RT1-u
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Involved Pathway
RT1-DA involved in several pathways and played different roles in them. We selected most pathways RT1-DA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RT1-DA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
RT1-DA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RT1-DA itself. We selected most functions RT1-DA had, and list some proteins which have the same functions with RT1-DA. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
RT1-DA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RT1-DA here. Most of them are supplied by our site. Hope this information will be useful for your research of RT1-DA.
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References
- Almeida-Suhett, CP; Li, Z; et al. Temporal Course of Changes in Gene Expression Suggests a Cytokine-Related Mechanism for Long-Term Hippocampal Alteration after Controlled Cortical Impact. JOURNAL OF NEUROTRAUMA 31:683-690(2014).
- Grieb, B; Engler, G; et al. High-Frequency Stimulation of the Subthalamic Nucleus Counteracts Cortical Expression of Major Histocompatibility Complex Genes in a Rat Model of Parkinson's Disease. PLOS ONE 9:-(2014).
