RPS6KA6

  • Official Full Name

    ribosomal protein S6 kinase, 90kDa, polypeptide 6

  • Overview

    This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010]

  • Synonyms

    RPS6KA6;ribosomal protein S6 kinase, 90kDa, polypeptide 6;RSK4;PP90RSK4;ribosomal protein S6 kinase alpha-6;RSK-4;p90RSK6;p90-RSK 6;S6K-alpha 6;S6K-alpha-6;ribosomal S6 kinase 4;90 kDa ribosomal protein S6 kinase 6

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Insect Cells
  • Sf9 Cells
  • HEK293
  • Sf21 Cells
  • His
  • GST
  • Non
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
RPS6KA6-2436H Recombinant Human RPS6KA6, His-tagged E.coli Human His C-117aa
RPS6KA6-3329H Recombinant Human RPS6KA6 protein(Met1-Leu745), GST-tagged Insect Cells Human GST Full L. 1-745 a.a.
RPS6KA6-30418TH Recombinant Human RPS6KA6 Human Non
RPS6KA6-427H Recombinant Human RPS6KA6, GST-tagged, Active Sf9 Cells Human GST
RPS6KA6-674HCL Recombinant Human RPS6KA6 cell lysate Insect Cells Human Non
RPS6KA6-0317H Recombinant Human RPS6KA6 Protein (M1-L745), Tag Free Insect Cells Human Non M1-L745
RPS6KA6-0318H Recombinant Human RPS6KA6 Protein (M1-L745), GST tagged Insect Cells Human GST M1-L745
RPS6KA6-2307H Recombinant Human RPS6KA6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
RPS6KA6-4242HF Active Recombinant Full Length Human RPS6KA6 Protein, GST-tagged Sf21 Cells Human GST Full L. 1-745
Rps6ka6-5612M Recombinant Mouse Rps6ka6 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    RPS6KA6 involved in several pathways and played different roles in them. We selected most pathways RPS6KA6 participated on our site, such as MAPK signaling pathway,Oocyte meiosis,mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Long-term potentiation CALM1,PLCB3,CALM4,PRKACB,GRIN1,CALM2,PPP1CA,ATF4,GRIN2C,RAF1
    Neurotrophin signaling pathway CALM1,CALML3,SHC1,CAMK2A,PIK3CB,GAB1,RAC1,PLCG1,SHC2,NFKB1
    Oocyte meiosis CUL1,CPEB4,PPP1CB,INS1,YWHAE2,CALM4,YWHAG1,CPEB1B,SPDYB,PPP3R1
    mTOR signaling pathway AKT1,MTOR,ULK3,TSC1,RRAGD,RPS6KB1B,RPS6KAL,PTENB,PIK3CD,PRKCBA
    Progesterone-mediated oocyte maturation ARAF,RPS6KA2,PRKACAA,GNAIA,CCNB1,GNAI2,GNAI1,ANAPC5,CCNA1,AKT2
    Insulin resistance PYGMA,NFKBIAB,PRKAB2,NR1H2,ACACB,AKT3A,PRKAG2,IL6,RPS6KA3A,SLC27A1A
    MAPK signaling pathway CACNB1,GADD45BA,MAPK11,FGF16,MAP4K2,PDGFRB,PAK2A,TAOK1,CACNA2D1A,PLA2G4F

    Protein Function

    RPS6KA6 has several biochemical functions, for example, ATP binding,magnesium ion binding,protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA6 itself. We selected most functions RPS6KA6 had, and list some proteins which have the same functions with RPS6KA6. You can find most of the proteins on our site.

    Function Related Protein
    magnesium ion binding IDH1,ENO1A,TDP2,IRAK3,TDP2B,ATP8B5,MTHFD2,GSS,RPS6KA4,SNCA
    ATP binding AARS2,CDK14,EIF4A1A,MCM5,MYO5B,CKMT2,DYRK1B,MYO1C,TLK1B,NLRP4E
    protein kinase activity SIK2A,MAP3K4,MAP3K11,CDK14,CSNK1G3,SYK,CAMK2D1,TEX14,KITB,RIPK4
    ribosomal protein S6 kinase activity RPS6KB2,RPS6KB1,RPS6KA3,RPS6KA3B,RPS6KA2,RPS6KB1B,RPS6KA1,ALPK2,RPS6KA4,RPS6KA3A

    Interacting Protein

    RPS6KA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA6.

    HSP90AB1;DNAJC13;MED24;RPLP1;CLEC3B;CENPB;RXRA;NR4A1;DNMT1;MAPK3;MASP1;UFM1;LMO4;MPP1;CEBPZ;RBPJ;FZD5;DHX34;ADIRF;ZNF746

    Resources

    Research Area

    Apoptosis Intracellular Kinases
    Ribosomal Protein S6 Kinases (RSK)

    References

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