RPGR
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Official Full Name
retinitis pigmentosa GTPase regulator -
Synonyms
CRD;RP3;COD1;PCDX;RP15;XLRP3;orf15;CORDX1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RPGR-2234HCL | Recombinant Human RPGR 293 Cell Lysate | HEK293 | Human | Non |
|
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| RPGR-4522H | Recombinant Human RPGR protein, hFc-tagged | Mammalian cell | Human | Fc | 54-367aa |
|
Involved Pathway
RPGR involved in several pathways and played different roles in them. We selected most pathways RPGR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RPGR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RPGR has several biochemical functions, for example, guanyl-nucleotide exchange factor activity,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPGR itself. We selected most functions RPGR had, and list some proteins which have the same functions with RPGR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ABCA1,CD48,C10orf119,ARL4D,TAF15,TEK,XPO1,BLOC1S4,EPHB1,TAP1 |
| guanyl-nucleotide exchange factor activity | RAPGEFL1,ARHGEF17,PRSS56,ARHGEF11,ARHGEF1B,GDPGP1,RANGRF,SH2D3A,ARFGEF2,TRIOA |
| poly(A) RNA binding | HELZ,RPL27,CTNNA1,OASL1,THOC4,EDF1,TOP1,RPL28,LUC7L3,SEC23IP |
Interacting Protein
RPGR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPGR here. Most of them are supplied by our site. Hope this information will be useful for your research of RPGR.
PDE6D;RPGRIP1;Pde6d;Arl3;b4dyc6_human;Arl2
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References
- Murga-Zamalloa, C; Swaroop, A; et al. Multiprotein Complexes of Retinitis Pigmentosa GTPase Regulator (RPGR), a Ciliary Protein Mutated in X-Linked Retinitis Pigmentosa (XLRP). RETINAL DEGENERATIVE DISEASES: LABORATORY AND THERAPEUTIC INVESTIGATIONS 664:105-114(2010).
- He, S; Parapuram, SK; et al. Retinitis pigmentosa GTPase regulator (RPGR) protein isoforms in mammalian retina: Insights into X-linked retinitis pigmentosa and associated cillopathies. VISION RESEARCH 48:366-376(2008).
