RNPC3
-
Official Full Name
RNA-binding region (RNP1, RRM) containing 3 -
Overview
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. -
Synonyms
RNPC3;RNA-binding region (RNP1, RRM) containing 3;RNA-binding protein 40;FLJ20008;KIAA1839;RBM40;U11/U12 snRNP 65K;AI447568;MGC188204;RNA binding protein 40;2810441O16Rik;C030014B17Rik;FLJ25070;KIAA183;RNA binding motif protein 40;RNA binding region (RNP1 RRM) containing 3;RNA binding region containing protein 3;RNP;U11/U12 65K;U11/U12 small nuclear ribonucleoprotein 65 KDa protein;U11/U12 snRNP 65 KDa protein;U11/U12-65K;RNA recognition protein;RNA-binding motif protein 40;RNA-binding region-containing protein 3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RNPC3-14362M | Recombinant Mouse RNPC3 Protein | Mammalian Cell | Mouse | His |
|
|
| RNPC3-3686Z | Recombinant Zebrafish RNPC3 | Mammalian Cell | Zebrafish | His |
|
|
| RNPC3-2261HCL | Recombinant Human RNPC3 293 Cell Lysate | HEK293 | Human | Non |
|
|
| RNPC3-7698M | Recombinant Mouse RNPC3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| RNPC3-7698M-B | Recombinant Mouse RNPC3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
RNPC3 involved in several pathways and played different roles in them. We selected most pathways RNPC3 participated on our site, such as Gene Expression,Processing of Capped Intron-Containing Pre-mRNA,mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA Splicing - Minor Pathway | PRPF8,YBX1,SNRNP48,PDCD7,ZCRB1,ZMAT5,SF3B2,SNRNP25,SNRNP35,SF3B4 |
| Gene Expression | MTA2,ADAR,ZNF483,ZNF671,ZNF2,ADAT3,TRMT6,NR0B2A,TET1,HNRNPA0B |
| mRNA Splicing | SF3A1,PDCD7,SNRNP48,HNRNPH1L,HNRNPL,HNRNPH1,SFRS3A,ZCRB1,PTBP1A,HNRNPUL1 |
| Processing of Capped Intron-Containing Pre-mRNA | SF3A3,HNRNPF,SF3A1,SUGP1,THOC4,HNRNPA0B,HNRNPL2,RNPS1,SLBP,HNRNPH1 |
Protein Function
RNPC3 has several biochemical functions, for example, U12 snRNA binding,nucleotide binding,pre-mRNA intronic binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNPC3 itself. We selected most functions RNPC3 had, and list some proteins which have the same functions with RNPC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| U12 snRNA binding | RBM41 |
| pre-mRNA intronic binding | PRPF8,SOX9,RBM41,EP300,HNRNPA2B1,RBM4 |
| nucleotide binding | GNA11B,RHOU,STK35L,ABCA5,TTLL9,CSNK1DB,RBM4.1,EEF1A1A,ABCB4,PARN |
Interacting Protein
RNPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNPC3.
PRNP;pepB;SMAD2;Srp72;PTBP3
Resources
Related Services
Related Products
References
