RNF25

  • Official Full Name

    ring finger protein 25

  • Overview

    The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination.

  • Synonyms

    RNF25;ring finger protein 25;E3 ubiquitin-protein ligase RNF25;AO7;FLJ13906;ring finger protein AO7

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • Chicken
  • E.coli
  • Mammalian Cell
  • HEK293
  • Mammalian cells
  • HEK293T
  • His
  • Myc&DDK
  • Non
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
RNF25-2508H Recombinant Human RNF25 protein, His-tagged E.coli Human His 111-459 aa
RNF25-11400Z Recombinant Zebrafish RNF25 Mammalian Cell Zebrafish His
RNF25-14341M Recombinant Mouse RNF25 Protein Mammalian Cell Mouse His
RNF25-2917C Recombinant Chicken RNF25 Mammalian Cell Chicken His
RNF25-671H Recombinant Human RNF25 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
RNF25-1526HCL Recombinant Human RNF25 cell lysate Human Non
RNF25-1218HFL Recombinant Full Length Human RNF25 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
RNF25-1899H Recombinant Human RNF25 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
RNF25-1899H-B Recombinant Human RNF25 Protein Pre-coupled Magnetic Beads HEK293 Human
RNF25-2894H Recombinant Human RNF25 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Rnf25-5556M Recombinant Mouse Rnf25 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
RNF25-7681M Recombinant Mouse RNF25 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
RNF25-7681M-B Recombinant Mouse RNF25 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    RNF25 involved in several pathways and played different roles in them. We selected most pathways RNF25 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System UBE2U,HECTD3,RNF144B,CTSD,KIF26A,CSK,UBE2J2,LILRA2,SIGLEC9,KLRF1
    presentation TRIM69,PJA1,UBE2L6,FBXO44,GAN,SPSB2,CD207,RBCK1,RNF4,UBE2F
    Proteasome degradation CMTM2A,RNF34,IWS1,ASB18,MKRN1,TRIM69,RNF182,TRAF7,ASB6,STUB1
    Class I MHC mediated antigen processing &amp DZIP3,RNF41,FBXO3,FBXO44,RNF34,LRR1,SEC23A,ASB14,ARIH2,KLHL21
    Antigen processing: Ubiquitination &amp ASB7,HUWE1,RNF138,LRRC41,TRIM39,ASB2,DZIP3,BLMH,UBR1,UBE2E3
    TNF-alpha/NF-kB Signaling Pathway TANK,PFDN2,FAF1,ZFAND5,DPF2,PPP1R13L,TNIP1,RNF216,NKIRAS2,USP2
    Tryptophan metabolism AOX2P,TPH1A,GCDH,ALDH9A1,CMTM2A,KMO,CYP2F1,TPH1,HADHAB,ALDH7A1
    Immune System NCKIPSD,ABI1A,CFHL4,B2ML,SPSB4,KIF26A,IRF6,UBE2E3,LAIR2,CTSH

    Protein Function

    RNF25 has several biochemical functions, for example, NF-kappaB binding,ligase activity,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF25 itself. We selected most functions RNF25 had, and list some proteins which have the same functions with RNF25. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity RNF4,UBE2D1B,TRAIP,STUB1,BRCA1,RNF19A,NEURL3,EGR2,RING1,C12orf51
    ubiquitin-protein transferase activity AMFR,SIAH1A,TRIM37,FEM1A,FBXO7,UBE2L6,UBE2H,LNX1,TNFAIP3,RLIM
    ubiquitin protein ligase activity AKTIP,CDC34,HERC4,HECW2,TRIM11,HECTD1,FANCF,MED24,RNF222,ANAPC11
    zinc ion binding TRIM3B,ZDHHC17,RNF148,GATA2B,ZDHHC23B,PGLYRP5,MEP1B,PHF15,TRIM38,ZSWIM2
    NF-kappaB binding NFKBIA,GSK3B,ANKRD42,RELA,PSMA6,SNAI1A,COMMD7,CPNE1,BRMS1,RPS3

    Interacting Protein

    RNF25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF25 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF25.

    UBE2D1;UBE2E1;UBE2D3;UBE2D2;UBE2E3;UBE2D4;UBE2L6;TRIM27;UBE2U;UBE2E2

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