RNF212
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Official Full Name
ring finger protein 212 -
Overview
This gene encodes a RING finger protein that may function as a ubiquitin ligase. The encoded protein may be involved in meiotic recombination. This gene is located within a linkage disequilibrium block and polymorphisms in this gene may influence recombination rates. Alternate splicing results in multiple transcript variants. -
Synonyms
RNF212;ring finger protein 212;hypothetical protein LOC285498 , LOC285498;FLJ38841;Hypothetical protein LOC285498;RNF 212;ZHP3;OTTHUMP00000147525;OTTHUMP00000217464;OTTHUMP00000217466
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RNF212-2343H | Recombinant Human RNF212, His-tagged | E.coli | Human | His | 1-192aa | |
| RNF212-674H | Recombinant Human RNF212 Protein, His-tagged | E.coli | Human | His |
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| RNF212-1525HCL | Recombinant Human RNF212 cell lysate | Human | Non |
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| RNF212-3436H | Recombinant Human RNF212 protein, GST-tagged | E.coli | Human | GST | 1-297aa |
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Involved Pathway
RNF212 involved in several pathways and played different roles in them. We selected most pathways RNF212 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF212 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
RNF212 has several biochemical functions, for example, ligase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF212 itself. We selected most functions RNF212 had, and list some proteins which have the same functions with RNF212. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | TTLL2,SH3RF1,ZFP91,RNF138,TRIM27,TTLL9,MID1,TRIM63,PELI2,RNF135 |
| zinc ion binding | KDM5A,ADAMTS4,P2RX2,WHSC1L1,RGN,Car8,ZDHHC5A,SHARPIN,DTX3L,PHF23B |
Interacting Protein
RNF212 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF212 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF212.
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References
- Fujiwara, Y; Matsumoto, H; et al. An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility. REPRODUCTION 149:67-74(2015).
- Oke, A; Anderson, CM; et al. Controlling Meiotic Recombinational Repair - Specifying the Roles of ZMMs, Sgs1 and Mus81/Mms4 in Crossover Formation. PLOS GENETICS 10:-(2014).
