RNF125
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Official Full Name
ring finger protein 125, E3 ubiquitin protein ligase -
Overview
This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. -
Synonyms
RNF125;ring finger protein 125, E3 ubiquitin protein ligase;ring finger protein 125;E3 ubiquitin-protein ligase RNF125;FLJ20456;T-cell RING activation protein 1;T-cell ring protein identified in activation screen;TRAC1;TRAC-1;MGC21737
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RNF125-2646H | Recombinant Human RNF125 protein, His-tagged | E.coli | Human | His | 1 - 232 aa | |
| RNF125-14294M | Recombinant Mouse RNF125 Protein | Mammalian Cell | Mouse | His |
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| RNF125-859C | Recombinant Cynomolgus RNF125 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| RNF125-545HCL | Recombinant Human RNF125 lysate | HEK293 | Human | Non |
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| RNF125-2119H | Recombinant Human RNF125 Protein (1-232 aa), GST-tagged | E.coli | Human | GST | 1-232 aa |
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| RNF125-602C | Recombinant Cynomolgus Monkey RNF125 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| RNF125-602C-B | Recombinant Cynomolgus Monkey RNF125 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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| RNF125-7647M | Recombinant Mouse RNF125 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RNF125-7647M-B | Recombinant Mouse RNF125 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RNF125 involved in several pathways and played different roles in them. We selected most pathways RNF125 participated on our site, such as RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF125 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RIG-I-like receptor signaling pathway | MAP3K7,RIPK1,IFNA4,AZI2,DHX58,MAPK12,MAPK14A,IFNA14,RNF207B,IFNA8 |
Protein Function
RNF125 has several biochemical functions, for example, ligase activity,ubiquitin-protein transferase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF125 itself. We selected most functions RNF125 had, and list some proteins which have the same functions with RNF125. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | UBE2G1,LMO7,UBR3,FEM1A,TRIM23,IRAK1,RNF4,RNF181,CMTM2A,MDM2 |
| zinc ion binding | RNF144AB,CHURC1,BAZ1B,COP1,TRIM74,NAPEPLD,ZPR1,RNF44,RPH3A,MICAL1 |
| ligase activity | HUWE1,UHRF1,BRCA1,RNF126,ZFP91,TRIM13,UBE1Y1,UCHL1,CNOT4,UBR4 |
Interacting Protein
RNF125 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF125 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF125.
UBE2L6;UBE2L3;HIP2;PML;UBE2D1;UBE2D3;UBE2K;UBE2N;UBE2D2;prfA;UBE2U;TRIM46;UBE2W;CHFR;UBE2E2;PCGF1;UBE2D4
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