RNASEH2C
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Official Full Name
ribonuclease H2, subunit C -
Overview
This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008] -
Synonyms
RNASEH2C;ribonuclease H2, subunit C;AGS3;AYP1;ribonuclease H2 subunit C;RNase H2 subunit C;RNase H1 small subunit;ribonuclease HI subunit C;aicardi-Goutieres syndrome 3 protein
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- HEK293
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RNASEH2C-2328H | Recombinant Human RNASEH2C, His-tagged | E.coli | Human | His | 1-164aa | |
| AYP1-1051H | Recombinant Human AYP1 protein, GST-tagged | Wheat Germ | Human | GST |
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| RNASEH2C-14274M | Recombinant Mouse RNASEH2C Protein | Mammalian Cell | Mouse | His |
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| RNASEH2C-3914R | Recombinant Rhesus monkey RNASEH2C Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| RNASEH2C-7491Z | Recombinant Zebrafish RNASEH2C | Mammalian Cell | Zebrafish | His |
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| RNASEH2C-1473HF | Recombinant Full Length Human RNASEH2C Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 164 amino acids |
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| RNASEH2C-3731R | Recombinant Rhesus Macaque RNASEH2C Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| RNASEH2C-3731R-B | Recombinant Rhesus Macaque RNASEH2C Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RNASEH2C-7635M | Recombinant Mouse RNASEH2C Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RNASEH2C-7635M-B | Recombinant Mouse RNASEH2C Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RNASEH2C involved in several pathways and played different roles in them. We selected most pathways RNASEH2C participated on our site, such as DNA replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNASEH2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Replication | RNASEH2B,RFC1,MCM4,MCM6L,SSBP1,RPA3,POLE3,POLD2,GINS4,RNASEH1 |
Protein Function
RNASEH2C has several biochemical functions, for example, RNA-DNA hybrid ribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNASEH2C itself. We selected most functions RNASEH2C had, and list some proteins which have the same functions with RNASEH2C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA-DNA hybrid ribonuclease activity | RNASEH2A,APEX1,FEN1,RNASEH2B,RNASEH1,EXO1 |
Interacting Protein
RNASEH2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNASEH2C here. Most of them are supplied by our site. Hope this information will be useful for your research of RNASEH2C.
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