RIMS1
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Official Full Name
regulating synaptic membrane exocytosis 1 -
Overview
The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. The encoded protein may be part of the protein scaffold of the cell. Defects in this gene are a cause of cone-rod dystrophy type 7 (CORD7). Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RIMS1;regulating synaptic membrane exocytosis 1;CORD7, RAB3 interacting protein 2 , RAB3IP2;regulating synaptic membrane exocytosis protein 1;KIAA0340;Rab3 interacting molecule;RIM;RIM1;RAB3-interacting protein 2;rab-3-interacting protein 2;rab
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RIMS1-2307H | Recombinant Human RIMS1, GST-tagged | E.coli | Human | GST | 912-1028aa | |
| RIMS1-14230M | Recombinant Mouse RIMS1 Protein | Mammalian Cell | Mouse | His |
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| RIMS1-5047R | Recombinant Rat RIMS1 Protein | Mammalian Cell | Rat | His |
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| RIMS1-4706R | Recombinant Rat RIMS1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| RIMS1-4706R-B | Recombinant Rat RIMS1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RIMS1-7608M | Recombinant Mouse RIMS1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RIMS1-7608M-B | Recombinant Mouse RIMS1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RIMS1 involved in several pathways and played different roles in them. We selected most pathways RIMS1 participated on our site, such as Synaptic vesicle cycle,Retrograde endocannabinoid signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with RIMS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synaptic vesicle cycle | ATP6V0D2,SNAP25,ATP6V0E1,ATP6V1G1,ATP6V1E2,NAPA,STX1A,ATP6V1D,ATP6V1A,UNC13A |
| Retrograde endocannabinoid signaling | GABRP,PRKCG,MAPK8,GRIA3,ITPR1,GABRR2,GNG8,GABRA1,GABRA6,GABRG1 |
Protein Function
RIMS1 has several biochemical functions, for example, GTPase regulator activity,Rab GTPase binding,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RIMS1 itself. We selected most functions RIMS1 had, and list some proteins which have the same functions with RIMS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase regulator activity | WAS,GPSM2L,TSC1,RGS14A,RUNDC3A,RALGDS,ARL2BP,TSC1B,TSC1A,RGS12B |
| poly(A) RNA binding | SUPT5H,GTPBP1,TWF2,REXO4,S100A4,RBM27,C1orf35,TAF15,DDX5,RPS17 |
| ion channel binding | ARRB1,ACTN2,FKBP1B,YWHAQ,PIRT,CDH5,TCAP,CALM2,CALM3,ID2 |
| metal ion binding | CARS,MINA,ARID2,UNC13B,CHPF,S100T,NR5A1A,ZNF624,TATDN1,ZNF644A |
| protein binding | BBOX1,COMMD8,DISC1,SOCS1,AKAP6,GRB7,CARD10,C1QBP,PFKL,DRG2 |
| Rab GTPase binding | RAB11FIP5,RABGGTA,TBC1D20,EVI5,PDE6D,MYO5B,SGSM3,EXPH5,AP3M1,RAB3GAP2 |
Interacting Protein
RIMS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RIMS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RIMS1.
ABL1;FYN;NCK1;GRB2;SMAD2;LRRK1;pi3p
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