RILP

  • Official Full Name

    Rab interacting lysosomal protein
  • Overview

    This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.
  • Synonyms

    RILP;Rab interacting lysosomal protein;rab-interacting lysosomal protein;FLJ31193;PP10141
Cat.# Product name Source (Host) Species Tag Protein Length Price
RILP-2303H Recombinant Human RILP protein, His-tagged E.coli Human His 101-401 aa
RILP-1179H Recombinant Full Length Human RILP Protein, MYC/DDK-tagged HEK293 Human Myc&DDK Full L.
Rilp-5512M Recombinant Full Length Mouse Rilp Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK Full L.
RILP-5625H Recombinant Human RILP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK

    Involved Pathway

    RILP involved in several pathways and played different roles in them. We selected most pathways RILP participated on our site, such as Phagosome,Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with RILP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Salmonella infection CCL4L2,MAPK14B,MAPK14A,NLRC4,NFKB1,MAPK12A,RAC1A,ARPC5L,DYNC2H1,RELA
    Phagosome TUBA7L,TUBA8L,RAB5B,TUBA3E,NCF4,TUBB6,FCGR3,MHC2DAB,BMA1,TLR2

    Protein Function

    RILP has several biochemical functions, for example, Rab GTPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RILP itself. We selected most functions RILP had, and list some proteins which have the same functions with RILP. You can find most of the proteins on our site.

    Function Related Protein
    Rab GTPase binding MLPH,RABGEF1,RAB11FIP4,DENND5A,SGSM3,SYTL4,NGFR,CFAP45,MYO5A,GAS8
    protein binding BRD4,TBC1D20,C19orf80,FOXR2,LGALS3,CNBP,WDR92,ATF2,ACAT2,SCARB2

    Interacting Protein

    RILP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RILP here. Most of them are supplied by our site. Hope this information will be useful for your research of RILP.

    RAB7A;VPS41;VPS39;VPS16;VPS11;VPS18;KPNA2;hemN;RCHY1

    Resources

    References

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