RICTOR
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Official Full Name
RPTOR independent companion of MTOR, complex 2 -
Overview
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth;factor-derived signals to regulate cell growth (Sarbassov et al., 2004 (PubMed 15268862)). -
Synonyms
RICTOR;RPTOR independent companion of MTOR, complex 2;rapamycin-insensitive companion of mTOR;AVO3;KIAA1999;MGC39830;PIA;pianissimo;rapamycin insensitive companion of mTOR;hAVO3;AVO3 homolog;TORC2-specific protein AVO3;mAVO3;DKFZp686B11164
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RICTOR-3004H | Recombinant Human RICTOR protein, His-tagged | E.coli | Human | His | 1-183 aa | |
| RICTOR-3306H | Recombinant Human RICTOR protein, His-tagged | E.coli | Human | His | 1-183 aa | |
| RICTOR-14220M | Recombinant Mouse RICTOR Protein | Mammalian Cells | Mouse | His |
|
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| RICTOR-31328TH | Recombinant Human RICTOR | Wheat Germ | Human | Non | 98 amino acids |
|
| RICTOR-1509HCL | Recombinant Human RICTOR cell lysate | Human | Non |
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| RICTOR-001H | Recombinant Human RPTOR independent companion of MTOR complex 2 Protein, His-tagged | E.coli | Human | His | 1-250 aa |
|
| RICTOR-301236H | Recombinant Human RICTOR 9 protein, GST-tagged | E.coli | Human | GST | Met1-Val51 |
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| RICTOR-7602M | Recombinant Mouse RICTOR Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RICTOR-7602M-B | Recombinant Mouse RICTOR Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RICTOR involved in several pathways and played different roles in them. We selected most pathways RICTOR participated on our site, such as mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RICTOR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mTOR signaling pathway | VEGFAB,PIK3R3A,PRR5,AKT2L,HIF1AB,ULK1,RRAGD,EIF4BB,PIK3CB,PDPK1 |
Protein Function
RICTOR has several biochemical functions, for example, enzyme activator activity,protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RICTOR itself. We selected most functions RICTOR had, and list some proteins which have the same functions with RICTOR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ribosome binding | ABCF1,YTHDF1,SEC61A1,EIF2A,MTRF1L,EIF2S1,BAG6,HSPA5,OLA1,ICT1 |
| protein binding | DEFB121,TBX5,FAM46C,PDE9A,CETN2,DBNL,APOA1BP,KSR1,CCNC,C14orf104 |
| enzyme activator activity | PSAPL1,ASAP2,CLPSL1,RAB3GAP2,GTF3C4,GM1679,MMP16,APOA5,MGST2,MMP17 |
| protein kinase binding | ATF2,CALM3,HDAC4,GDF3,TELO2,BAG5,MAP2K6,BORA,BCL2L14,RPS6 |
Interacting Protein
RICTOR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RICTOR here. Most of them are supplied by our site. Hope this information will be useful for your research of RICTOR.
MTOR
RICTOR Related Signal Pathway
Resources
Related Services
Related Products
References
- Limon, JJ; So, L; et al. mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:E5076-E5085(2014).
- Jin, YP; Valenzuela, NM; et al. Everolimus Inhibits Anti-HLA I Antibody-Mediated Endothelial Cell Signaling, Migration and Proliferation More Potently Than Sirolimus. AMERICAN JOURNAL OF TRANSPLANTATION 14:806-819(2014).
