RHOBTB1
-
Official Full Name
Rho-related BTB domain containing 1 -
Overview
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. -
Synonyms
RHOBTB1;Rho-related BTB domain containing 1;rho-related BTB domain-containing protein 1;KIAA0740;3110048G13Rik;AI173445;AI573858;MGC107538;1700008H16Rik;AV350930;MGC33059;MGC33841;OTTHUMP00000019662;OTTHUMP00000019663;Rho related BTB domain containing 1;Rho related BTB domain containing protein 1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Chicken
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
RHOBTB1 involved in several pathways and played different roles in them. We selected most pathways RHOBTB1 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOBTB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | RHOBTB2,PML,SOCS1A,SMURF2,RFWD2,WWP2,CBLC,RHOBTB2A,PRPF19,BIRC8 |
Protein Function
RHOBTB1 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOBTB1 itself. We selected most functions RHOBTB1 had, and list some proteins which have the same functions with RHOBTB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RAB1A,RAB23,ARL4AA,SPAG1,GIMAP3,EEF1A1L1,NKIRAS2,RALBB,ARFRP1,RAP2B |
Interacting Protein
RHOBTB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOBTB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOBTB1.
HSP90AB1;Cep152
Resources
Related Services
Related Products
References
- Xu, RS; Wu, XD; et al. The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 42:676-682(2013).
- Song, RL; Gu, JH; et al. Inhibition of osteoclast bone resorption activity through osteoprotegerin-induced damage of the sealing zone. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:856-862(2014).
