RGS9
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Official Full Name
regulator of G-protein signaling 9 -
Overview
This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways;by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells;and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in;bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RGS9;regulator of G-protein signaling 9;regulator of G protein signalling 9;MGC26458;MGC111763;PERRS;regulator of G protein signalling 9L;regulator of G protein signaling 9L;RGS9L;R9AP;regulator of G-protein signalling 9
Recombinant Proteins
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- His
- His&T7
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RGS9-5024R | Recombinant Rat RGS9 Protein | Mammalian Cell | Rat | His |
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| RGS9-8182H | Recombinant Human RGS9 protein, His & T7-tagged | E.coli | Human | His&T7 | Met1~Val296 |
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| Rgs9-8183M | Recombinant Mouse Rgs9 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Met1~Trp296 |
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| RGS9-2367HCL | Recombinant Human RGS9 293 Cell Lysate | HEK293 | Human | Non |
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| RGS9-4683R | Recombinant Rat RGS9 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| RGS9-4683R-B | Recombinant Rat RGS9 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RGS9-6664H | Recombinant Human RGS9 Protein (Met1-Val296), N-His tagged | E.coli | Human | His | Met1-Val296 |
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Involved Pathway
RGS9 involved in several pathways and played different roles in them. We selected most pathways RGS9 participated on our site, such as Phototransduction,Cocaine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cocaine addiction | GRIN2D,PRKACG,ATF4,CREB3L1,DRD2,PRKACA,CREB3L3,CDK5,GPSM1,DRD1 |
| Phototransduction | SLC24A1,CALM1A,CALML3,PDE6A,GNB1B,RGS9B,PDE6G,GNB4B,CALM1B,OPN1MW4 |
Protein Function
RGS9 has several biochemical functions, for example, G-protein beta-subunit binding,GTPase activator activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS9 itself. We selected most functions RGS9 had, and list some proteins which have the same functions with RGS9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein beta-subunit binding | CCT5,F2RL1,RASD2,GNG13,F2R,RGS11,OPRM1,GNG2,RGS7 |
| signal transducer activity | STAT5A,ADORA2AB,TAS1R2.1,OLFR146,TAAR4,OLFR508,TAAR14F,GNB4,OMPB,AVP |
| GTPase activator activity | RGS3,SOS1,ARRB1,GIT1,TBC1D19,EVI5,RABGAP1,RGS12,RASAL1,CDC42EP5 |
Interacting Protein
RGS9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS9 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS9.
Dlg4;HSP90AB1
Resources
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References
- Danielsson, A; Ponten, F; et al. The Human Pancreas Proteome Defined by Transcriptomics and Antibody-Based Profiling. PLOS ONE 9:-(2014).
- Xie, KQ; Martemyanov, KA; et al. Control of striatal signaling by G protein regulators. FRONTIERS IN NEUROANATOMY 5:-(2011).
