RGS7
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Official Full Name
regulator of G-protein signaling 7 -
Overview
Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene. -
Synonyms
RGS7;regulator of G-protein signaling 7;regulator of G protein signalling 7;OTTHUMP00000037994;Regulator of G-protein signaling RGS7;Regulator of G-protein signalling 7
Recombinant Proteins
- Human
- Chicken
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RGS7-2282H | Recombinant Human RGS7, His-tagged | E.coli | Human | His | C-term-349aa | |
| RGS7-4179C | Recombinant Chicken RGS7 | Mammalian Cell | Chicken | His |
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| RGS7-5021R | Recombinant Rat RGS7 Protein | Mammalian Cell | Rat | His |
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| RGS7-664Z | Recombinant Zebrafish RGS7 | Mammalian Cell | Zebrafish | His |
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| RGS7-2369HCL | Recombinant Human RGS7 293 Cell Lysate | HEK293 | Human | Non |
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| RGS7-3429H | Recombinant Human RGS7 protein, His-tagged | E.coli | Human | His | 1-487aa |
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| RGS7-4680R | Recombinant Rat RGS7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| RGS7-4680R-B | Recombinant Rat RGS7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Rgs7-5500M | Recombinant Mouse Rgs7 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RGS7-5832H | Recombinant Human RGS7 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
RGS7 involved in several pathways and played different roles in them. We selected most pathways RGS7 participated on our site, such as Calcium Regulation in the Cardiac Cell,G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by GPCR | ARHGEF18,UTS2,DCLRE1B,OXGR1,VIP2,GPR65,OPN1LW1,INSL5,XK,OR4D2 |
| G alpha (i) signalling events | OPN1MW,OPN1LW2,ADORA3,CCR7,APLNR,GPR55A,POMCB,OPN1SW1,RGS21,OPN5 |
| Signal Transduction | ARHGAP6,NMBA,APOA4A,ANXA1B,ARHGEF25,GUCA1E,PRDM4,ARHGAP9,LINGO1,ARHGAP24 |
| Calcium Regulation in the Cardiac Cell | YWHAQ,GJB4,CX30.3,ADRA1D,GJB2,CHRM3,KCNJ3,RGS14,GJB1,ADRA1B |
| Myometrial Relaxation and Contraction Pathways | ACTA1,IGFBP4,IGFBP6,RGS10,PKIB,CORIN,RGS16,RGS19,RAMP3,CRHR1 |
| GPCR downstream signaling | CALCRL,DRD4,QRFPR,NMBA,GNA13,CCL35.2,FPR-RS6,CCK,VIP,PPY |
Protein Function
RGS7 has several biochemical functions, for example, G-protein beta-subunit binding,GTPase activator activity,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS7 itself. We selected most functions RGS7 had, and list some proteins which have the same functions with RGS7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D2B,RABEP1,TBC1D8B,RASA4,TSC2,RGS9A,PLEKHG6,ARHGAP44,SIPA1L2,RALGAPA1 |
| signal transducer activity | PLEKHB1,PLCH1,IKBKG,DRD2B,OLFR13,GPR15,GPR89,PTGER4A,LGALS1,TRAF3 |
| G-protein beta-subunit binding | CCT5,RASD2,GNG2,F2R,F2RL1,RGS9,GNG13,OPRM1,RGS11 |
Interacting Protein
RGS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS7.
FOS;HSP90AB1;PLCG1;CRK;MCM7
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References
- Chen, FS; Shim, H; et al. Functional Redundancy of R7 RGS Proteins in ON-Bipolar Cell Dendrites. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51:686-693(2010).
- Ajit, SK; Ramineni, S; et al. RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling. CELLULAR SIGNALLING 19:723-730(2007).
