RGS21

  • Official Full Name

    regulator of G-protein signaling 21

  • Overview

    Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.

  • Synonyms

    RGS21;regulator of G-protein signaling 21;regulator of G protein signalling 21;regulator of G-protein signalling 21
Cat.# Product name Source (Host) Species Tag Protein Length Price
RGS21-29966TH Recombinant Human RGS21, His-tagged E.coli Human His 152 amino acids
RGS21-3615H Recombinant Human RGS21, His-tagged E.coli Human His

    Involved Pathway

    RGS21 involved in several pathways and played different roles in them. We selected most pathways RGS21 participated on our site, such as G alpha (i) signalling events,G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCR downstream signaling CRHB,CRH,RLN3A,OPN1SW1,ARHGEF16,AMCF-II,ANXA1A,OXGR1A.1,TRPC3,KISS1
    G alpha (q) signalling events TRIO,OXTRL,QRFPR,APPB,RASGRP2,TAE1,KALRNB,AGTR1,GPR68,RGS19
    Signal Transduction IFT88,ARHGEF16,RNF41,ROR2,ARHGAP40,DHRS3A,NMT1A,ACKR4,USP9,FAM13B
    Signaling by GPCR PPY,GPR120,INSL3,SST1.1,UTS2D,NTS,ARHGEF25,OR4D2,GPR31B,CCK
    Gastrin-CREB signalling pathway via PKC and MAPK LPAR2B,FFAR3,QRFPR,EDN3,FPR-RS3,TRIO,ANXA1B,RGS19,GCGB,EDNRAB
    G alpha (i) signalling events RGS4,CCL35.2,OXGR1,HCAR1-2,PENKB,LPAR2A,OPN1LW,FPR-RS6,SOUL3,RGS1

    Protein Function

    RGS21 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS21 itself. We selected most functions RGS21 had, and list some proteins which have the same functions with RGS21. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity TBC1D25,ARHGAP33,AGFG2,TBC1D10C,ARHGAP10,ARHGEF15,ACAP3,RGS12B,RINL,STARD8

    Interacting Protein

    RGS21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS21 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS21.

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