RFX2
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Official Full Name
regulatory factor X, 2 (influences HLA class II expression) -
Overview
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008] -
Synonyms
RFX2;regulatory factor X, 2 (influences HLA class II expression);DNA-binding protein RFX2;regulatory factor X 2;DNA binding protein RFX2;trans-acting regulatory factor 2;HLA class II regulatory factor RFX2
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RFX2-2264H | Recombinant Human RFX2, GST-tagged | E.coli | Human | GST | C-term-300aa | |
| RFX2-14113M | Recombinant Mouse RFX2 Protein | Mammalian Cells | Mouse | His |
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| RFX2-2085Z | Recombinant Zebrafish RFX2 | Mammalian Cells | Zebrafish | His |
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| RFX2-5008R | Recombinant Rat RFX2 Protein | Mammalian Cells | Rat | His |
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| RFX2-2399HCL | Recombinant Human RFX2 293 Cell Lysate | HEK293 | Human | Non |
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| RFX2-369H | Recombinant Human RFX2 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| RFX2-4667R | Recombinant Rat RFX2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| RFX2-4667R-B | Recombinant Rat RFX2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Rfx2-5480M | Recombinant Mouse Rfx2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| RFX2-7550M | Recombinant Mouse RFX2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RFX2-7550M-B | Recombinant Mouse RFX2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RFX2 involved in several pathways and played different roles in them. We selected most pathways RFX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RFX2 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX2 itself. We selected most functions RFX2 had, and list some proteins which have the same functions with RFX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | HOXC3A,SIM1A,KLF5,SOX6,ZFP541,SP1,H2AFVA,Rhox5,C3orf37,NEUROG1 |
| transcription factor activity, sequence-specific DNA binding | TBX16,NFIA,HSF2,ATF3,HIF1A,GATA1,ZNF831,NR2F1B,SMAD3,NR2F6A |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | TCF3B,NPAS4,H2AFZ,GABPA,ZFP639,NR3C1,SALL1,MYBL2,CEBPG,SOX10 |
Interacting Protein
RFX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX2.
RFX6;MDFI
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