REV3L
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Official Full Name
REV3-like, catalytic subunit of DNA polymerase zeta (yeast) -
Overview
Protein reversionless 3-like (REV3L) also known as DNA polymerase zeta catalytic subunit (POLZ) is an enzyme that in humans is encoded by the REV3L gene. -
Synonyms
REV3L;REV3-like, catalytic subunit of DNA polymerase zeta (yeast);REV3 (yeast homolog) like, catalytic subunit of DNA polymerase zeta;DNA polymerase zeta catalytic subunit;polymerase;DNA;zeta;POLZ;Catalytic subunit of DNA polymerase zeta;Polymerase DNA zeta;RAD54 like;REV3 yeast homolog like;Sez4;Yeasthomolog of Rev 3;hREV3;OTTHUMP00000017933;OTTHUMP00000017934;Rev-3, yeast, homolog-like (polymerase, DNA, zeta);REV3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| REV3L-14091M | Recombinant Mouse REV3L Protein | Mammalian Cell | Mouse | His |
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| REV3L-7535M | Recombinant Mouse REV3L Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| REV3L-7535M-B | Recombinant Mouse REV3L Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
REV3L involved in several pathways and played different roles in them. We selected most pathways REV3L participated on our site, such as Metabolic pathways,Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with REV3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | FANCE,STRA13,RMI2,UBE2T,RPA3,EME1,WDR48,PMS2,SLX1B,TOP3A |
| Metabolic pathways | NT5C1AA,CDS1,CHIA.3,PLA2G2F,UAP1L1,CYP19A1,PRODH2,NOS2B,PDHA1B,GLS2 |
Protein Function
REV3L has several biochemical functions, for example, 3-5 exonuclease activity,4 iron, 4 sulfur cluster binding,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by REV3L itself. We selected most functions REV3L had, and list some proteins which have the same functions with REV3L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 4 iron, 4 sulfur cluster binding | RSAD1,IREB2,MOCS1,NTHL1,RTEL1,MUTYH,TYW1B,NDUFS8B,NDUFV1,NDUFS8A |
| nucleotide binding | PKN1B,ATAD5B,ITPK1A,ARF6B,GNA15.4,PABPC4,ABCA1B,SIK2A,ABCG2B,CHD8 |
| 3-5 exonuclease activity | EXD1,RAD9,APLF,EXOSC10,TREX1,WRN,POLG,RAD9B,REXO2,POLA1 |
| metal ion binding | ZNF180,PPM1NB,ZNF576.2,ZNF45,BMX,ZNF706,DMRTA1,ZDHHC23B,BMPR2,LNX2 |
| nucleic acid binding | CMTR1,GTF3A,SRSF7A,ZBTB12.2,PLAGL2,DDX51,ZBTB7C,ATF7B,BRD9,ZFP191 |
| transferase activity | CAMK1GA,PRKAR1AA,MAP2K4B,UGT5B4,GALNT11,EXT1A,TAOK3,AANAT,CEPT1B,IGF1RA |
| iron-sulfur cluster binding | AIFM4,ABAT,GLRX3,ELP3,RPS3,PRIM2,RSAD1,CISD3,RTEL1,CMAH |
| nucleotidyltransferase activity | POLE2,GKUP,UAP1L1,CTU2,TERT,POLN,POLR3B,PRIM2,CCDC111,PAPSS1 |
| DNA binding | PRDM9,RFXAP,SOX19B,PAX6,ZFP668,PIN4,ZNF2,IRX5A,ZNF544,SIX6B |
Interacting Protein
REV3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REV3L here. Most of them are supplied by our site. Hope this information will be useful for your research of REV3L.
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