RDH5
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Official Full Name
retinol dehydrogenase 5 (11-cis/9-cis) -
Overview
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. -
Synonyms
RDH5;retinol dehydrogenase 5 (11-cis/9-cis);RDH1, retinol dehydrogenase 5 (11 cis and 9 cis);11-cis retinol dehydrogenase;HSD17B9;SDR9C5;short chain dehydrogenase/reductase family 9C;member 5;11 cis RDH;11 cis retinol dehydrogenase;9 cis retinol specific dehydrogenase;FLJ39337;FLJ97089;RDH 5;RDH1;Retinol dehydrogenase 1;Retinol dehydrogenase 5 (11 cis/9 cis);Retinol dehydrogenase 5;Short chain dehydrogenase/reductase family 9C member 5;11-cis RDH;OTTHUMP00000242975;OTTHUMP00000242976;OTTHUMP00000242988;9-cis-retinol specific dehydrogenase;retinol dehydrogenase 5 (11-cis and 9-cis);short chain dehydrogenase/reductase family 9C, member 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RDH5-2240H | Recombinant Human RDH5, GST-tagged | E.coli | Human | GST | 19-290aa | |
| RDH5-3231Z | Recombinant Zebrafish RDH5 | Mammalian Cells | Zebrafish | His |
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| RDH5-6278C | Recombinant Chicken RDH5 | Mammalian Cells | Chicken | His |
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| RDH5-2435HCL | Recombinant Human RDH5 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
RDH5 involved in several pathways and played different roles in them. We selected most pathways RDH5 participated on our site, such as Retinol metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with RDH5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Retinol metabolism | RDH12,UGT2B7,RPE65C,UGT2A1,CYP2C70,UGT1A3,ALDH1A1,CYP2C39,Aldh1a7,BCMO1 |
Protein Function
RDH5 has several biochemical functions, for example, retinol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RDH5 itself. We selected most functions RDH5 had, and list some proteins which have the same functions with RDH5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| retinol dehydrogenase activity | ADH1,AKR1C3,ADH4,BMP2,RDH10,HSD17B6,DHRS9,RDH8,ADH7,RDH11 |
Interacting Protein
RDH5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RDH5 here. Most of them are supplied by our site. Hope this information will be useful for your research of RDH5.
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