RAX2
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Official Full Name
retina and anterior neural fold homeobox 2 -
Overview
This gene encodes a homeodomain-containing protein that plays a role in eye development. Mutation of this gene causes age-related macular degeneration type 6, an eye disorder resulting in accumulations of protein and lipid beneath the retinal pigment epithelium and within the Bruchs membrane. Defects in this gene can also cause cone-rod dystrophy type 11, a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity, followed by the degeneration of rod photoreceptor cells, which progresses to night blindness and the loss of peripheral vision. -
Synonyms
RAX2;retina and anterior neural fold homeobox 2;RAXL1, retina and anterior neural fold homeobox like 1;retina and anterior neural fold homeobox protein 2;MGC15631;ARMD6;CORD11;Macular degeneration, age related 6, included;Q50 type retinal homeobox;QRX;Retina and anterior neural fold homeobox like 1;Q50-type retinal homeobox protein;retina and anterior neural fold homeobox-like protein 1;RAXL1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAX2-5680C | Recombinant Chicken RAX2 | Mammalian Cell | Chicken | His |
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| RAX2-2491HCL | Recombinant Human RAX2 293 Cell Lysate | HEK293 | Human | Non |
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| RAX2-4353H | Recombinant Human RAX2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| RAX2-6144HF | Recombinant Full Length Human RAX2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 184 amino acids |
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Involved Pathway
RAX2 involved in several pathways and played different roles in them. We selected most pathways RAX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RAX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
RAX2 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAX2 itself. We selected most functions RAX2 had, and list some proteins which have the same functions with RAX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | LMX1BA,MEOX2B,DMRT3,HSF5,SIX1,SMAD3,NKX2.9,HOXB1B,NCOR1,DLX6A |
Interacting Protein
RAX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAX2.
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