RAPGEF6
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Official Full Name
Rap guanine nucleotide exchange factor (GEF) 6 -
Overview
Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene. -
Synonyms
RAPGEF6;Rap guanine nucleotide exchange factor (GEF) 6;PDZ domain containing guanine nucleotide exchange factor (GEF) 2 , PDZGEF2;rap guanine nucleotide exchange factor 6;PDZ GEF2;RA GEF 2;PDZ domain-containing guanine nucleotide exchange factor 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAPGEF6-1632H | Recombinant Human RAPGEF6, GST-tagged | E.coli | Human | GST | 1-164aa | |
| RAPGEF6-499H | Recombinant Human RAPGEF6 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Rapgef6-5379M | Recombinant Mouse Rapgef6 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| RAPGEF6-5811H | Recombinant Human RAPGEF6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
RAPGEF6 involved in several pathways and played different roles in them. We selected most pathways RAPGEF6 participated on our site, such as Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAPGEF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | LPAR5,VAV2,FGF3,MAGI2,PARD6B,PIK3CA,PRKCI,FARP2,GNAI2,INSR |
Protein Function
RAPGEF6 has several biochemical functions, for example, GTP-dependent protein binding,Ras GTPase binding,guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAPGEF6 itself. We selected most functions RAPGEF6 had, and list some proteins which have the same functions with RAPGEF6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| guanyl-nucleotide exchange factor activity | EIF2B5,DOCK1,PREX1,RPGR,ARHGEF37,DENND4B,KNDC1,GCGR,TRIOA,RIC8B |
| GTP-dependent protein binding | ARFIP2,GCHFR,RAB38,EEA1,MRAS,RAB32,HPS6,GCH1,RAPGEF5,PPIAL4A |
| protein binding | DDX6,TXN2,FAM72A,PLCB1,KPNB1,INVS,HIST1H2AM,TJAP1,ITGB3BP,GHRHR |
| Ras GTPase binding | RAP1GAP,SH3BP4,RAPGEF4,RASGRP3,MLLT4,SPHK2,MAPKAP1,CIB1,RAP1A,MAP2K1 |
| phosphatidic acid binding | MAPKAP1,PLCD1,JPH2,COMMD1,PACSIN2,NRGN,MICALL1,UQCC3,MARK1,SESTD1 |
Interacting Protein
RAPGEF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAPGEF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAPGEF6.
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