RAP1GDS1
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Official Full Name
RAP1, GTP-GDP dissociation stimulator 1 -
Overview
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity;(Riess et al., 1993 (PubMed 8262526)). -
Synonyms
RAP1GDS1;RAP1, GTP-GDP dissociation stimulator 1;rap1 GTPase-GDP dissociation stimulator 1;SmgGDS;Exchange factor smgGDS;GDS1;GTP-GDP dissociation stimulator 1;Highly similar to RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1;MGC118859;MGC118861;RAP1;SMG GDS protein;SMG P21 stimulatory GDP/GTP exchange protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAP1GDS1-2822C | Recombinant Chicken RAP1GDS1 | Mammalian Cell | Chicken | His |
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| RAP1GDS1-2526HCL | Recombinant Human RAP1GDS1 293 Cell Lysate | HEK293 | Human | Non |
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| RAP1GDS1-4168H | Recombinant Human RAP1GDS1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| RAP1GDS1-468H | Recombinant Human RAP1GDS1 protein, GST-tagged | E.coli | Human | GST | 176-406 aa |
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| Rap1gds1-5374M | Recombinant Mouse Rap1gds1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RAP1GDS1-773H | Recombinant Human RAP1GDS1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
RAP1GDS1 involved in several pathways and played different roles in them. We selected most pathways RAP1GDS1 participated on our site, such as Regulation of RAC1 activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAP1GDS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of RAC1 activity | SPATA13,ARHGAP1,ARHGAP17,ABR,EPS8,DEF6,RALBP1,CHN2,DOCK6,PREX2 |
Protein Function
RAP1GDS1 has several biochemical functions, for example, GTPase activator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAP1GDS1 itself. We selected most functions RAP1GDS1 had, and list some proteins which have the same functions with RAP1GDS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | AP2B1,TTC8,WARS,OCA2,PRKRIR,PECAM1,FAM154A,PPP2R2C,CCBE1,APBB1IP |
| GTPase activator activity | TBC1D22B,ARHGDIG,RABEP1,ARHGAP20,TBC1D3,DOCK1,RABGAP1,TSC2,ARHGAP32,SRGAP2A |
Interacting Protein
RAP1GDS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAP1GDS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAP1GDS1.
MBIP;PLEKHB1;EGFR;CDC42;RAC1;MBIP;PUF60;ZNF451;pi3p;CDK2
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References
- Hsieh, YF; Liu, GY; et al. Transglutaminase 2 Contributes to Apoptosis Induction in Jurkat T Cells by Modulating Ca2+ Homeostasis via Cross-Linking RAP1GDS1. PLOS ONE 8:-(2013).
