RAGE
-
Official Full Name
renal tumor antigen -
Overview
This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. -
Synonyms
RAGE;renal tumor antigen;renal tumor antigen;MOK protein kinase;MOK;MAPK/MAK/MRK overlapping kinase;renal cell carcinoma antigen (MOK protein kinase);Renal tumor antigen 1;EC 2.7.11.22;RAGE1;RAGE-1;OTTHUMP00000227853;OTTHUMP00000227854;OTTHUMP00000227855
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|
Involved Pathway
RAGE involved in several pathways and played different roles in them. We selected most pathways RAGE participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RAGE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RAGE has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RAGE itself. We selected most functions RAGE had, and list some proteins which have the same functions with RAGE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
RAGE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAGE here. Most of them are supplied by our site. Hope this information will be useful for your research of RAGE.
Resources
Research Area
Immune Regulatory Molecules on Endothelial CellsCytokine and Growth Factor Receptors on VSMC
Inflammatory Mediators
Blood-brain Barrier Transporters
Alzheimer's Disease
Diabetic Peripheral Neuropathy
ROS and Stress Resistance
Tumor Antigens
Related Services
Related Products
References
- Sharaf, H; Matou-Nasri, S; et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:429-441(2015).
- Rodriguez-Teja, M; Gronau, JH; et al. AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival. JOURNAL OF PATHOLOGY 235:581-592(2015).
