RAB40C
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Official Full Name
RAB40C, member RAS oncogene family -
Overview
The 21 kDa guanine-nucleotide binding proteins (K-Ras, H-Ras and N-Ras) cycle between active (GTP-bound) and inactive (GDP-bound) forms. Receptor tyrosine kinases and G-protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway -
Synonyms
RAB40C;RAB40C, member RAS oncogene family;RAS like, family 8, member C , RASL8C;ras-related protein Rab-40C;RARL;RAR like;RAS-like GTPase;rar-like protein;RAR (RAS like GTPASE) like;RAS-like, family 8, member C;SOCS box-containing protein RAR3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RAB40C-3772Z | Recombinant Zebrafish RAB40C | Mammalian Cells | Zebrafish | His |
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| RAB40C-4067C | Recombinant Chicken RAB40C | Mammalian Cells | Chicken | His |
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| RAB40C-7036H | Recombinant Human RAS, GST-tagged | E.coli | Human | GST | Full length |
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| RAB40C-1454HCL | Recombinant Human RAB40C cell lysate | Human | Non |
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Involved Pathway
RAB40C involved in several pathways and played different roles in them. We selected most pathways RAB40C participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB40C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
RAB40C has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB40C itself. We selected most functions RAB40C had, and list some proteins which have the same functions with RAB40C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GDP binding | RAN,RAB3B,RAB8A,RRAS,RAB12,RHOA,RAB10,EIF2B1,RAP2B,RAB9A |
| GTP binding | RALAA,SEPT5,GNA13A,ARL4AB,RAC1A,RERGL,GNAZ,RAB4B,RND3A,IRGM |
| GTPase activity | GNA15,TUBA8L4,TUBAL3,EEF1A1L2,RAB38,RAP1GAP,MX1,GTPBP1,RAB21,ATL1 |
Interacting Protein
RAB40C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB40C here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB40C.
TCEB1;TCEB2;CUL5;RNF7;PSD;TOE1
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References
- Tan, R; Wang, WJ; et al. Small GTPase Rab40c Associates with Lipid Droplets and Modulates the Biogenesis of Lipid Droplets. PLOS ONE 8:-(2013).
- Solaimani, P; Damoiseaux, R; et al. Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. TOXICOLOGICAL SCIENCES 136:107-119(2013).
