PYGO2
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Official Full Name
pygopus homolog 2 (Drosophila) -
Overview
Pygopus homolog 2 is a protein that in humans is encoded by the PYGO2 gene. -
Synonyms
PYGO2;pygopus homolog 2 (Drosophila);pygopus homolog 2;1190004M21Rik;FLJ33226;Pygo2 protein;PYGO2_HUMAN;pygopus 2;OTTHUMP00000035488
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PYGO2-3396Z | Recombinant Zebrafish PYGO2 | Mammalian Cell | Zebrafish | His |
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| PYGO2-1451HCL | Recombinant Human PYGO2 cell lysate | Human | Non |
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| PYGO2-1932H | Recombinant Human PYGO2 protein, His & GST-tagged | E.coli | Human | His&GST | Leu171~Gly406 |
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| PYGO2-6686H | Recombinant Human PYGO2 Protein (Leu171-Gly406), N-His tagged | E.coli | Human | His | Leu171-Gly406 |
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Involved Pathway
PYGO2 involved in several pathways and played different roles in them. We selected most pathways PYGO2 participated on our site, such as Deactivation of the beta-catenin transactivating complex,Formation of the beta-catenin:TCF transactivating complex,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PYGO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TCF dependent signaling in response to WNT | SOX13,LGR4,ASH2L,LGR6,C,SOX7,DACT1,SRY,SOX4B,RYK |
| Signaling by Wnt | CCDC88C,SOX9A,PRICKLE1,CBY1,TLE3B,FMNL3,HECW1B,HECW1,CDC73,SOX4B |
| Formation of the beta-catenin:TCF transactivating complex | CDC73,H3F3B.1,TLE3,TLE3B,BCL9,PYGO1,TLE1,BCL9L,H3F3D,RBBP5 |
| Signal Transduction | RSPO2,RLN2,PYYA,AKR1C6,SHB,USP34,NOG1,CRABP1B,GPR177,RGS17 |
| Deactivation of the beta-catenin transactivating complex | SOX13,SOX6,TLE3B,ASH2L,TLE1,SRY,TLE3,BCL9,SOX9A,TLE4 |
Protein Function
PYGO2 has several biochemical functions, for example, chromatin binding,histone acetyltransferase regulator activity,histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PYGO2 itself. We selected most functions PYGO2 had, and list some proteins which have the same functions with PYGO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KLC2,CCS,STK4,ORC1L,RPL28,DCDC2,DCD,PITX1,GLYAT,C22orf39 |
| histone binding | CD1D,NOC2L,BRD7,HIST2H3C,H3F3A,HINFP,MCM2,WDTC1,HIST2H4,RCC1 |
| zinc ion binding | G2E3,KMT2E,RNF144AA,ESRRA,TRIM61,RNF6,RTN4IP1,ZDHHC1,ADAM2,ZMIZ1A |
| chromatin binding | HDAC7,PLAC8,BAZ1B,TCF7L1A,ERCC6,ANKRD2,FOXN4,MEIS1,SSRP1,CHAF1B |
| histone acetyltransferase regulator activity | EID1 |
Interacting Protein
PYGO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PYGO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PYGO2.
BCL9;JRK;Bcl9l;CDC73
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