PURB

  • Official Full Name

    purine-rich element binding protein B

  • Overview

    This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

  • Synonyms

    PURB;purine-rich element binding protein B;transcriptional activator protein Pur-beta;PURBETA;purine-rich element-binding protein B

Recombinant Proteins

  • Human
  • Bacillus subtilis
  • Mouse
  • Rat
  • E.coli
  • E. coli or Yeast
  • Mammalian Cell
  • HEK293
  • GST
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PURB-2072H Recombinant Human PURB, GST-tagged E.coli Human GST 1-312aa
PURB-0186B Recombinant Bacillus subtilis PURB protein, His-tagged E. coli or Yeast Bacillus subtilis His
PURB-13723M Recombinant Mouse PURB Protein Mammalian Cell Mouse His
PURB-193H Recombinant Human PURB, His-tagged E.coli Human His 1-312aa
PURB-4850R Recombinant Rat PURB Protein Mammalian Cell Rat His
PURB-4509R Recombinant Rat PURB Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
PURB-4509R-B Recombinant Rat PURB Protein Pre-coupled Magnetic Beads HEK293 Rat
PURB-7302M Recombinant Mouse PURB Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PURB-7302M-B Recombinant Mouse PURB Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PURB involved in several pathways and played different roles in them. We selected most pathways PURB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PURB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PURB has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,SMAD binding,mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PURB itself. We selected most functions PURB had, and list some proteins which have the same functions with PURB. You can find most of the proteins on our site.

    Function Related Protein
    transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding NFKB1,FOXO3,MITF,CGGBP1,FOXD3,FERD3L,ETV3,AEBP1,E2F7,KLF6A
    transcription factor binding BRD7,ATF7,JUNB,TRIM6,KCNA3,MED1,FOXA2,NFKBIA,RARA,H2-AB1
    single-stranded DNA binding SSBP3B,WBP11,SSBP1,IGHMBP2,RAD51D,RPA4,TDP2B,RPA3,MCM7,TSN
    poly(A) RNA binding MECP2,CPSF6,MRPL11,RPL11,ENO1,HDLBP,RPS14,ZCCHC8,CDK11B,CNBP
    SMAD binding BMPR1A,PML,COL1A2,SOD3,SKOR1B,MAGI2,DAB2,SKOR1,TOB1,SKILB
    RNA polymerase II regulatory region sequence-specific DNA binding JARID2,GATA6,ZNF711,RARG,MNT,NFIL3,ZNF480,ZNF548,PHF21B,CDX1A
    mRNA binding EIF4A3,RPS5,DOM3Z,TYMS,SSB,RPL13A,CPSF6,RBM25,PAIP2,SLBP

    Interacting Protein

    PURB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PURB here. Most of them are supplied by our site. Hope this information will be useful for your research of PURB.

    CSNK2A1;q8te30_human;ESR2;UVRAG

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