PTTG1IP
-
Official Full Name
pituitary tumor-transforming 1 interacting protein -
Overview
The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1. -
Synonyms
PTTG1IP;pituitary tumor-transforming 1 interacting protein;C21orf1, C21orf3;pituitary tumor-transforming gene 1 protein-interacting protein;PBF;AI314311;AU018448;C79540;MGC36923;1810010L20Rik;C21orf1;C21orf3;chromosome 21 open reading frame 1;Pituitary tumor transforming 1 interacting protein;Pituitary tumor transforming gene 1 protein interacting protein;Pituitary tumor transforming gene protein binding factor;PTTG binding factor;Putative surface glycoprotein C21orf1 precursor;OTTHUMP00000115272;OTTHUMP00000115273;PTTG-binding factor;pituitary tumor-transforming gene protein-binding factor
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His&GST
- His
- Non
- His&Fc&Avi
Involved Pathway
PTTG1IP involved in several pathways and played different roles in them. We selected most pathways PTTG1IP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTTG1IP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PTTG1IP has several biochemical functions, for example, molecular_function,p53 binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTTG1IP itself. We selected most functions PTTG1IP had, and list some proteins which have the same functions with PTTG1IP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| p53 binding | CDKN2A,GATA1,ZNF385B,SETD7,MDM2,RNF20,HSPD1,EP300,CHD8,ZNF346 |
| protein binding | SASS6,STON2,GLS2,C3orf39,KRTAP10-5,UBXN6,XPA,IL1R1,ZFPM1,TPCN2 |
| molecular_function | LHFPL2A,TMEM57B,TCL1B3,VWA5B2,TTC9B,RSPH3B,NPAP1,MAGEB6,TMEM44,ANKRD10B |
Interacting Protein
PTTG1IP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTTG1IP here. Most of them are supplied by our site. Hope this information will be useful for your research of PTTG1IP.
LDLRAD1;CLEC7A;RAB4A;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate
Resources
Related Services
Related Products
References
