PTPRS
-
Official Full Name
protein tyrosine phosphatase, receptor type, S -
Overview
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. -
Synonyms
PTPRS;protein tyrosine phosphatase, receptor type, S;receptor-type tyrosine-protein phosphatase S;R-PTP-S;R-PTP-sigma;protein tyrosine phosphatase PTPsigma;receptor-type tyrosine-protein phosphatase sigma;protein tyrosine phosphatase, receptor type
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Mammalian cells
- E.coli
- HEK293T
- Mammalian Cell
- HEK293
- Insect Cell
- His
- GST
- Myc&DDK
- Non
- His&T7
- His&Fc&Avi
- His&Myc
Involved Pathway
PTPRS involved in several pathways and played different roles in them. We selected most pathways PTPRS participated on our site, such as ECM proteoglycans,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Extracellular matrix organization | DDR2,LEPREL1,PCOLCEA,CRTAP,COL17A1,MFAP3,P3H2,LRP4,COL13A1,COL4A6 |
| ECM proteoglycans | DAG1,MATN1,BGNA,LRP4,SPARC,ASPN,COL9A3,COL9A1,MUSK,COMP |
Protein Function
PTPRS has several biochemical functions, for example, protein binding,transmembrane receptor protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRS itself. We selected most functions PTPRS had, and list some proteins which have the same functions with PTPRS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane receptor protein tyrosine phosphatase activity | PTPRF,PTPRA,PTPRD,PTPRN2,EVLA,PTPRB,PTPN6,PTPRR,PTPRM,PTPRG |
| protein binding | DNALI1,ADAMTSL4,SLC52A2,KCTD5,RRAGB,APBA2,EEF1D,NOTCH1,SYAP1,NEDD4L |
Interacting Protein
PTPRS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRS here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRS.
PTPRN;EIF4A2;PTN;EEF1G;PFN2;SUMO2;CHD3;UNC119;TUBB2A;SETDB1;RAB35;UBR1;KAT5;FEZ1;UTP14A;CEP126
Resources
Related Services
Related Products
References
