PTPRQ
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Official Full Name
protein tyrosine phosphatase, receptor type, Q -
Overview
This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein;catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation;and differentiation. Mutations at this locus are associated with hearing loss. -
Synonyms
PTPRQ;protein tyrosine phosphatase, receptor type, Q;deafness, autosomal recessive 84 , DFNB84;phosphotidylinositol phosphatase PTPRQ;Protein tyrosine phosphatase RQ;PTPGMC1;PTP-RQ;R-PTP-Q;receptor-type tyrosine-protein phosphatase Q;protein-tyrosine phosphatase, receptor-type, expressed by glomerular mesangial cells;DFNB84
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PTPRQ-13705M | Recombinant Mouse PTPRQ Protein | Mammalian Cells | Mouse | His |
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| PTPRQ-4843R | Recombinant Rat PTPRQ Protein | Mammalian Cells | Rat | His |
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| PTPRQ-8107H | Recombinant Human PTPRQ protein, His & T7-tagged | E.coli | Human | His&T7 | Glu36~Thr294 |
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| PTPRQ-4502R | Recombinant Rat PTPRQ Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PTPRQ-4502R-B | Recombinant Rat PTPRQ Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PTPRQ-7290M | Recombinant Mouse PTPRQ Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PTPRQ-7290M-B | Recombinant Mouse PTPRQ Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PTPRQ involved in several pathways and played different roles in them. We selected most pathways PTPRQ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PTPRQ has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity,IDP phosphatase activity,JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRQ itself. We selected most functions PTPRQ had, and list some proteins which have the same functions with PTPRQ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein tyrosine phosphatase activity | MTMR1A,PTPN2B,PTPRG,MDP1,TIMM50,MTMR2,DUSP3B,PTPRFB,PTPN7,PTPN6 |
| IDP phosphatase activity | SGPP2,CTDSPL2B,SACM1L,CTDSPL2A,SACM1LA,NT5DC3,SACM1LB,TENC1,PXYLP1 |
| inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity | CTDSPL2A,PXYLP1,TENC1,SGPP2,SACM1LB,CTDSPL2B,SACM1L,ITPK1,SACM1LA,NT5DC3 |
| inositol-4,5-bisphosphate 5-phosphatase activity | PXYLP1,TENC1,CTDSPL2B,CTDSPL2A,SACM1L,NT5DC3,SACM1LB,SGPP2,SACM1LA |
| phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | NT5DC3,SACM1LB,TENC1,MTMR1A,SACM1LA,MTMR1,SACM1L,CTDSPL2B,MTMR2,SGPP2 |
| phosphoprotein phosphatase activity | PPTC7A,DUSP22A,PPP1CAA,PHPT1,PPP3CCA,TENC1,PPM1DB,PTPN11,PDXP,PPP1CBL |
| 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity | TENC1,SGPP2,CTDSPL2B,CTDSPL2A,SACM1LA,SACM1L,SACM1LB,PXYLP1,NT5DC3 |
| phosphatidylinositol-4-phosphate phosphatase activity | CTDSPL2B,FIG4,TENC1,PXYLP1,SACM1LB,NT5DC3,CTDSPL2A,SGPP2,SACM1LA,SACM1L |
| MAP kinase tyrosine/serine/threonine phosphatase activity | DUSP7,DUSP5,DUSP6,SACM1L,DUSP9,DUSP1,NT5DC3,DUSP16,SACM1LA,SGPP2 |
Interacting Protein
PTPRQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRQ here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRQ.
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